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This forum is for questions and support regarding your pet dogs!
You know your dog better than anyone else, so you are the best person to evaluate her quality of life. From what you write, it doesn't sound like she's suffering from pain. If she needs to lay low for a while, well, she's doing what she needs to do. All you can do is provide supportive care for the symptoms as long as you can. Bless you for already doing everything possible for her. :-)
Do everything you can to rule out a physical problem first. If she has a clean bill of health, see if you can hire a veterinary behaviorist to work with you both on the behavior issues. It's going to take a lot of patience, time and yes, money. But it's so worth it!
Med Help has a veterinarian to whom you can post your question as well. Look on the middle right side of this page and click on the Ask a Vet link to post your questions to Dr. Cheng.
breathing and heartrate down too much along w/the other meds and medical history...
Is your dog lying on its side...where normally curl up in a ball or lye differently??
Do your best with what you have....its very difficult to watch a dog decline and spiral down...just continue your comforting to your little friend and keep calm...
Get 2nd opinions, call ER vet hosps for advice and this forum has vet Dr. Cheng...
Good luck to you and yours...