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Optic Neuritis + Positive ANA 2560
by Eskander, Apr 22, 2008 04:18AM
Hi all
My wife (35 years old) was diagnosed with Optic Neuritis in the left eye in Sept. last year - 5 weeks after natural delivery of our second child. She never had ON before or complained of any neurological symptoms. She did an MRI and there were no signs of demylination or white matter. The Opthalmologist recommended to have no medications. Her sight returned from 6/6 to 6/24 with about 50% visual field loss in 6 months then stopped improving.
She did blood test in March this year and found very high titre of ANA 1:2560 with homogenuous pattern. Anti DNA was negative (normal levels). She saw a Rheumatologist. He did some more blood tests and examinations and excluded Lupus or any disorders. She doesnot have any joint pains or rash or any SLE symptoms. He said no connection between the ANA and the ON and she could be of those few on earth who have naturally high ANA.
She comes from the Middle East (MS is very rare) and has been living in Australia for 5 years so I dont think the caucasian statistics really apply.
I find it wierd to be of those few who get idiopathic ON and also of those few who have high ANA. I feel there is a connection there.
Any thoughts or recommendations?
Thanks
My wife (35 years old) was diagnosed with Optic Neuritis in the left eye in Sept. last year - 5 weeks after natural delivery of our second child. She never had ON before or complained of any neurological symptoms. She did an MRI and there were no signs of demylination or white matter. The Opthalmologist recommended to have no medications. Her sight returned from 6/6 to 6/24 with about 50% visual field loss in 6 months then stopped improving.
She did blood test in March this year and found very high titre of ANA 1:2560 with homogenuous pattern. Anti DNA was negative (normal levels). She saw a Rheumatologist. He did some more blood tests and examinations and excluded Lupus or any disorders. She doesnot have any joint pains or rash or any SLE symptoms. He said no connection between the ANA and the ON and she could be of those few on earth who have naturally high ANA.
She comes from the Middle East (MS is very rare) and has been living in Australia for 5 years so I dont think the caucasian statistics really apply.
I find it wierd to be of those few who get idiopathic ON and also of those few who have high ANA. I feel there is a connection there.
Any thoughts or recommendations?
Thanks
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