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polio vs parkinsons
by daughterwithquestions, Apr 26, 2008 08:27AM
my mother had polio as a child, now at 76 she is experiencing symptoms of parkinsons,
she has been on wellbutrin for about 8 years.
I am a family Nurse Practitioner, so feel lost, No one weems to be looking at this as a whole.
Where do I begin.
She has had MRI which was negative
She was started on Sinemet but her falls have increased- this past week she feel and hit her head, he falls are presenting quit differently from previous falls.
Please help with suggestions.
she has been on wellbutrin for about 8 years.
I am a family Nurse Practitioner, so feel lost, No one weems to be looking at this as a whole.
Where do I begin.
She has had MRI which was negative
She was started on Sinemet but her falls have increased- this past week she feel and hit her head, he falls are presenting quit differently from previous falls.
Please help with suggestions.
Post Comment
Carbidopa is dopa decarboxylase inhibitors. They help to prevent the metabolism of L-dopa before it reaches the dopaminergic neurons and are generally given as combination preparations of carbidopa/levodopa (e.g. Sinemet) There are also controlled release versions of Sinemet that spread out the effect of the L-dopa. Duodopa is a combination of levodopa and carbidopa, dispersed as a viscous gel. Entacapone inhibits the COMT enzyme, thereby prolonging the effects of L-dopa, and so has been used to complement L-dopa.
The dopamine-agonists bromocriptine, pergolide, pramipexole, ropinirole , cabergoline, apomorphine, and lisuride, are moderately effective.
Selegiline and rasagiline reduce the symptoms by inhibiting monoamine oxidase-B (MAO-B), which inhibits the breakdown of dopamine secreted by the dopaminergic neurons.
Best