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For how long have you been having this?
This sounds like a case of paronychia with an associated onychomycosis. Paronychia refers to a soft tissue infection of the skin surrounding the nail bed. Onychomycosis is a fungal infection affecting the nails .These requires prolonged oral medications that may require about 3 months of intake. Yeast infections affecting the nails are one of the most difficult to treat . Another differential will be psoriasis. Psoriatic lesions may also involve the nails however, this skin condition is usually associated with skin conditions in other parts of the body like the scalp, elbows and knees. In your case, the condition is more localized, so an infection may be likely.
Prolonged oral medications are usually needed for this type of condition. For how long have you taken your medications? Antibiotics may also be needed to treat the surrounding skin inflammation and infection.
At this point, a paronychia and onychomycosis are the primary differentials that I have in mind.