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Breast Cancer: Stage 3 & 4 Community

This patient support community is for discussions relating to breast cancer, biopsy, genetics, chemotherapy, hormone therapy, lumps, lumpectomy, lymph node dissection, lymphedema, mammograms, mastectomy, radiation therapy, reconstruction, self exams, and stage 3 and 4 treatments.
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LABC

by mohanplastic, May 04, 2008 08:33AM
What are the criteria for breast conservation surgery after Neoadjuvant chemotherapy for locally advanced breast cancer ?

Is it possible to do lumpectomy in a patient with LABC ?

Which is better if reconstruction of breast is needed after neoadjuvant chemotherapy, Immediate or delayed ?


Dr Mohan from Trissur, Kerala, India.
Member Comments (1)

by HeinrikMD, May 08, 2008 10:38AM
To: mohanplastic
Hi,

Criteria for performing breast conservation after neoadjuvant chemotherapy would be dependent on the surgeon’s capacity to excise the cancer with acceptable margins. There is a school of thought however of maximizing the chemotherapy before the operation – targeting a complete response (meaning all traces of cancer are gone), hence, the criteria before doing the surgery would be whether complete response has been achieved, or the set ceiling of drug doses has been reached.

Lumpectomy is indeed possible. But bear in mind, that radiation would be needed afterwards.

In terms of reconstruction, early reconstruction is emerging as preferred as it allows the surgery and the exposure to anesthetics to be limited to a single operation, remaining normal breast tissue tends to be more viable, and the aesthetic outcomes are better.
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