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Pediatric Endocrinology (Expert Forum)
Steriods and the apperance of hair in the groin
Answered by
Deanna L Aftab Guy, MD - Short Stature, thyroid, Pituitary abnormalit, Puberty concerns, Rapid Growth, Adrenal problems, Parathyroid abnormal, Rickets and bone dis
Vanderbilt Children’s Hospital
Nashville - TN
Questions in the Pediatric Endocrinology forum are answered by Dr. Deanna L Aftab Guy, affiliated with Vanderbilt Children's Hospital. Topics covered include adrenal problems, diabetes insipidus, menstrual irregularities, obesity, parathyroid abnormalities, pituitary abnormalities, puberty concerns, rapid growth, rickets and bone disease, short stature, and thyroid.
Steriods and the apperance of hair in the groin
by annar3069, May 05, 2008 10:47AM
My daughter is seven and a half. For the last few months she has been using an inhalor to prevent astma attacks. The active ingredient in the inhalor is Budesonide.Yesterday I noticed that she had some dark hairs aroud her anus and a little soft hair above her vagina. I don't know how long she's had it as she is of the age when she showers,etc without help. Is there a corelation between the use of steriods and hair growth that mimics, or is, puberty hair growth?
Doctor's Answer
by Deanna L Aftab Guy, MD, May 15, 2008 03:17PM
, May 15, 2008 03:17PM
To: annar3069
Even though there is indeed steroids in her inhaled medication these are glucocorticoids, not truly sex steroids, inhaled makes absorption into the body outside of the lungs much less than that taken by mouth.
Her hair in the pubic area is adrenarche, this is the adrenal gland making a little of its own hormones that cause body hair to become coarser and develop into pubic hair, also there may be affect on body odor or even axillary hair, it can happen as young as age 6.
It can still be normal just occuring a little early than others and not progress, this is premature adrenarche and is benign
But it is important to rule out the unsual causes like a block in the enzyme production on the adrenal glands, this is congenital adrenal hyperplasia, with a block in cortisol production, even partial there can be a build up of the hormones that lead to the end product of cortisol, like 17-OH progesterone, DHEAS, androstenedione, fancy names for things worth measuring,
I would first start with her pediatrician, an xray of the left wrist will tell us how mature her bones are to reassure us that there is not evidence of hormonal affect on her body, also getting a blood test depending on her findings is helpful.
The benign form of premature adrenarche is rather harmless, but needs still to be watched and weight control is essential, if she is obese this will trigger more of an effect and can lead to early puberty itself.
So work with your doc so they can decide what needs to be done next.
Her hair in the pubic area is adrenarche, this is the adrenal gland making a little of its own hormones that cause body hair to become coarser and develop into pubic hair, also there may be affect on body odor or even axillary hair, it can happen as young as age 6.
It can still be normal just occuring a little early than others and not progress, this is premature adrenarche and is benign
But it is important to rule out the unsual causes like a block in the enzyme production on the adrenal glands, this is congenital adrenal hyperplasia, with a block in cortisol production, even partial there can be a build up of the hormones that lead to the end product of cortisol, like 17-OH progesterone, DHEAS, androstenedione, fancy names for things worth measuring,
I would first start with her pediatrician, an xray of the left wrist will tell us how mature her bones are to reassure us that there is not evidence of hormonal affect on her body, also getting a blood test depending on her findings is helpful.
The benign form of premature adrenarche is rather harmless, but needs still to be watched and weight control is essential, if she is obese this will trigger more of an effect and can lead to early puberty itself.
So work with your doc so they can decide what needs to be done next.
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