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Thyroid  (Expert Forum)
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Dear Dr Lupo -Thyroid Antibodies
Answered by
Mark Lupo, M.D. - Thyroid Nodules, Thyroid Cancer, hyperthyroidism, hypothyroidism, Thyroid Ultrasound
Thyroid & Endocrine Center of Florida Sarasota - FL
Questions in the Thyroid forum are answered by Dr. Mark Lupo. Topics covered include goiter, graves disease, Hashimoto's thyroiditis, hyperthyroid, hypothyroid, thyroid cancers, thyroiditis, and thyroid stimulating hormone (TSH).

Dear Dr Lupo -Thyroid Antibodies

by Rite760, May 08, 2008 02:36PM
You have been most helpful in the past but I now how a confusing question. My TSH has been swinging from 1.0 to 4.6 and for the past year and you suspected Hashis and said to get antibodies done. I have now had them taken and here in the UK the normal reference range is 1 to 25. My doctor has said that if they were over 25 I would have hypothyroidism. But mine have come back at 1.0 which he said is still not normal as it is at the very end of the reference range and classed as borderline low. He said he has very rarely seen this result so low in anyone, and it indicates hyperthyroidism of ?cause and is sending me for further tests. Could you clarify why this means I have hyperthyroidism as he ran out of time to explain it to me and I'm concerned.

by Mark Lupo, M.D., May 08, 2008 05:25PM
The TSH swinging from 1-4.6 was suggestive of hashi, but not diagnostic.  The negative antibody (would not worry about it being 1.0 - that's still "negative") means there is not likely an immune system attack on the thyroid.  You do not have hyperthyroidism.  At this point would continue to monitor.  Sometimes dietary changes/fluctuations (ie, soy intake) can cause small TSH fluctuations like this.
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