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This forum is for questions regarding Dermatology issues, such as: skin rashes, acne, birthmarks, skin infections, rosacea, and general skin care.
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vitiligo and narrowband UVB

by ray1110, May 10, 2008 10:38PM
Tags: vitiligo
How effective in narrowband UVB + tacrolimus oint is this regimen better than PUVA sol or PUVA?
Thanks
Ray


This discussion is related to treatement for vitligo.
Member Comments

by BhumikaMD, Jun 06, 2008 02:19PM
Hi,

'Topical tacrolimus ointment (0.03% or 0.1%) is an effective alternative therapy for vitiligo, particularly when the disease involves the head and neck. Combination treatment with topical tacrolimus 0.1% plus the 308-nm Excimer laser is superior to monotherapy with the 308-nm Excimer laser monotherapy for UV-resistant vitiliginous lesions.

The combination of topical calcipotriene and narrowband UV-B or PUVA results in improvement appreciably better than achieve with monotherapy.

PUVA treatment (8-methoxypsoralen, 5-methoxypsoralen, trimethylpsoralen plus UVA) was often the most practical choice for treatment, especially in widespread vitiligo . However, 2 or 3 treatments per week for many months are required before repigmentation from perifollicular openings merges to produce confluent repigmentation.'

You could read more about this at the following link -

http://www.emedicine.com/DERM/topic453.htm

Let us know if you need any other information.

Regards.
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