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Eviromental Factors In Demyelinating Disease
by STUmld, Jun 17, 2008 11:43PM
I have for the last 2 years have a progression of strange pains throughout my body. It started with my left heel with severe stabbing pain that was extremely tender to the touch. As time progressed things have gotten worse. now for the last 6-8 months my mood has changed, I am anxious most of the time and my temper flairs. Also for the last 4 months my hand seem like they are tired and stiff from holding dumbbells all day long. I am constantly tired, unable to concentrate, and remember things. Lately I can sleep for 8 hours and still feel tired. I have had numerous tests done and my MSH and MMP9 are way out of whack. An MRI showed three abnormal bright spots on my brain. Can environmental factors cause these problems. Before 8 years ago I was an college athlete and a personal trainer so I was always in top shape.
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The scanning of the brain in MS would reflect perivascular inflammation and breakdown of blood-brain barrier. However, MS is difficult to diagnose in its early stages. Definite diagnosis cannot be made until other disease processes (differential diagnoses) have been ruled out and, in the case of relapsing-remitting MS, there is evidence of at least two anatomically separate demyelinating events separated by at least thirty days. In the case of primary progressive, a slow progression of signs and symptoms over at least 6 months is required
Magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) of the brain and spine is often used during the diagnostic process. MRI shows areas of demyelination (lesions) as bright spots on the image. Gadolinium, is administered intravenously to highlight active plaques and, by elimination, demonstrate the existence of historical lesions not associated with clinical symptoms. This can provide the evidence of chronic disease needed for a definitive diagnosis of MS.
Also, evaluation of Cerebrospinal fluid is recommended for the diagnosis of inflammatory conditions.
As such the co relation of Eviromental Factors In Demyelinating Disease is not fully established and remains obcure.
Best.