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Physical dependency can be an issue with Immodium over long-term use, but not addiction. So secondary withdrawal really shouldn't be an issue.
Nauty...........
Loperamide does not cross the blood-brain barrier - it has no impact on the brain and cannot result in addiction. It's action is limited to endogenous opioid receptors located along the the GI tract. That's why no matter how much you take it will never relieve general withdrawal symptoms.
Lucy