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Heart Disease Community

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Chronic ACE inhibitor treatment

by Elvis_P, Jul 06, 2008 09:34PM
After 11 years of treating malignant hypertension that sometimes reached 260/160 causing heart failure which was acute: 27% LVF but improved to 67% LVF with treatment of 40mg Lisinopril 4 Doxozosin 2.5 Bendroflurazide, now at 45 my kidneys are sloping off, 55 egrf weight unaccounted for.  I understand it is likely that due to the afferent/efferent atriol dilatation differential I may be able to get a 30% improvement in creatinine clearance by stopping ACE.  I want to do this before my GFR drops below 3rd stage failure but my cardiologist says ACE inhibitors have proven best right up to dialysis.  What other (if any) drugs would have similar BP lowering effects while preserving kidney function and giving back the 30% chronic ACE inhibitor treatment generally takes away.
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