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options to tamoxifen

by christy106, Jul 13, 2008 04:16AM
Three months ago I had a masectomy following a lumpectomy. I had ductal in situ in two seperate locations in the breast. My stage was stage zero. The lump was quite large however and was cribriform stage 2. I did not require chemo or radiation as it was prestage cancer. The cells were oestrogen positive.
I have been told by my Oncologist I need to take Tamoxifen. I am peri menopausal. I know this as over the last six months there have been changes to my menstrual cycle which was always very regular. Basically I do not want to take tamoxifen as I have had loop diathermy treatment in the past for abonormal cervix changes which were quite aggressive. I also have some eye problems following laser treatment. One Oncologist said I could take Arimidex but the other said this was no good as I am premenopausal. The treatment I would prefer would be Zoladex as I feel this would solve the problem of excess oestrogen. Do you know if this would suffice or second option not to take hormone therapy and hope the DCIS never returns? My breast tissue was checked on both breasts after the masectomy and there were no further areas of dcis. My other breast has been reduced in size to match the one which has been rebuilt with my stomach muscle.
Member Comments (1)

by DrNoopurMD, Jul 14, 2008 01:54AM
Hi,

Tamoxifen has been shown to be very effective in preventing recurrence and occurrence of breast cancer in women but it has also been found to increase the risk of cervical adenocarcinoma.
On the other hand Zoladex has been found to be effective in hormone sensitive breast cancers in pre and perimenopausal women. It seems to be a good option for you. Please discuss this with your oncologist in further detail. Take care!

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