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Hyperkeratosis is a thickening of the skin that occurs in women with brown skin. It is due to excessive accumulation of keratin in the outer layers of the skin. Thickening of the skin protects it against rubbing, pressure and irritation.
Most treatments are aimed at softening the keratin and removing the thickened skin. This may be accomplished with topical creams that contain as the active ingredient salicylic acid, alpha-hydroxy acid (lactic or glycolic acid), urea, or tretinoin.
Hyperpigmentation accompanies this type of hyperkeratosis. Hyperpigmentation is a common, usually harmless condition in which patches of skin become darker in color than the normal surrounding skin. This darkening occurs when an excess of melanin, the brown pigment that produces normal skin color, forms deposits in the skin.
Most prescription creams used to lighten the skin contain hydroquinone 2-4% to be applied on the darkened areas.
ref:http://www.brownskin.net/hyperkeratosis.html
ref: http://aocd.org/skin/dermatologic_diseases/hyperpigmentation.html