Thyroid Peroxidase TPO 767

[missouriangel]

So I have Hashi's. I just want to know the basics about Hashi's and what to expect? These are the only results I have right now. My nurse and doctor are going to call me in just a little while, and then I will know more. I will need to know what questions to ask while I have them on the phone?

         Test                                   Results                 Limits    
Thyroid Peroxidase (TPO) Ab       767 H IU/mL            0 - 34
        Results confirmed on dilution.
Antithyroglobulin Ab                      22    IU/mL            0 - 40
        Siemens (DPC) ICMA Methodology
There is something scribbled at the bottom by my doctor but I can not read it!

[estrelinha]

TSH, free T3 and free T4 (very important).

[dakota_girl]

I am new to the Hashi's thing as well so i'm curious to see the responses.

[AR-10]

It may get you on thyroid meds faster. The biggest difference it will make is in your doctor's attitude concerning future symptoms. He will be on the lookout for other autoimmune diseases. He will also be inclined to monitor your thyroid more frequently.

Ask what the scribbling is all about.

[Nancy927]

I'm looking for info too, trying to figure out what I have!  Good luck, I'll keep my eyes and ears open.

[missouriangel]

Other autoimmune diseases include...? Neuropathy? Connective Tissue Disease? Thyroiditis? Would this also maybe raise the reasons for removing my lesion? Just because my lesion isn't cancerous does that mean it isn't making me sick?

[AR-10]

There is a thread on the health pages with a link that explains Hashimoto's in it's many forms.

Hashimoto's is the most common form of hypothyroidism. Most people taking Synthroid or Armour or Levothyroxine have Hashimoto's. How well it is controlled depends on the patient, the gland, and how high the antibody counts are.

The more antibodies you have, the harder the disease is to control. Hashimoto's damages the gland over time. How much damage and how much time depends on how much antibodies.

Seeing a pattern here?

Some people with Hashimoto's live a lifetime without ever meeting an Endo or having major problems. Some people with Hashimoto's have their gland destroyed within five years. There is no "one size fits all" description of Hashimoto's.  

[AR-10]

Thyroiditis is a condition of the thyroid. It can be caused by Hashimoto's, but often there is another cause.

Once you have an autoimmune disease, like Hashimoto's, it is possible to develop another one. I don't know for sure, but it is possible certain forms of connective tissue disease may be autoimmune. Neuropathy can be a symptom of hypothyoidism. The neuropathy that you are asking about goes a little beyond Hashimoto's symptoms, I think. Most neuropathies associated with thyroid disease are reversible.

The lesion is typical damage from hashimoto's. Eventually your thyroid may become so damaged and diseased that it will have to be destroyed. Or maybe not. The path Hashimoto's takes can vary a lot from person to person.

As for the lesion in question, it is making you sick now, but it may clear up. Then it may flair up again. Or it may not. You may develop other lesions or nodules.

TPOab only has one function - screw up your thyroid.
Well, it can also be found alongside Lupus or Rheumatoid Arthritis, but it mainly eats your thyroid.

[estrelinha]

Connective Tissue Disease is probably autoimmune (Example: Rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), systemic sclerosis (SSc), polymyositis (PM), dermatomyositis (DM), mixed connective-tissue disease (MCTD), and Sjögren syndrome (SS) can present with similar clinical features, particularly during the first 12 months of symptoms; scleroderma, etc etc.), Neuropathy perhaps a complication of hypo or CTD. Ask your doctor, he knows (For sure he did all autoimmune tests).  ,

[missouriangel]

Wow, ok I think I understood that. I'm amazed. Ok AR-10, it is just so unpredictable it could do whatever it wants, it has no rhyme or reason. Well atleast I can understand and except that. Ok estrelinha, my doc told me he suspected Fibro, RA, Lupus, SLE, SSc, PM, DM, SS, and even Lyme so he did some blood work and spoke to my neurologist. On my next visit he officially diagnosed me with Neuropathy, and told me about the discovery of the CTD on my Upper GI.