Procarin patch-anything new known?

[kowgirlkathy]

It's now August 2008.  I can only find old research and comments on using Procarin.
Anything new ?
K!


This discussion is related to Procarin.

[kwbellingham]

Prokarin Procarin has worked for me..First off, it is a God send….I have had MS for 25 years & this is the best I have felt since first diagnosed.

My first 5 years I had problems walking…that passed…then since then major fatigue. My sister called me to let me know of a show she had watched with a women talking about Prokarin…and of course I looked into it right away..I emailed Elaine quite a few times for info…then I contacted my Insurance Co. many times to make sure they would cover the Prokarin & with help from Elaine they did and still do. I have tried every vitamin, diet, remedies and on and on that were said to conquer fatigue. I was tired all the time…would do maybe 10 minutes of housework & was completely worn out..My poor husband came home from work every night, and I was in the same spot…lying on the couch.

It was only about 2 weeks after starting the Prokarin that I could tell a difference. I did not know I could or would ever feel this good again…but I feel absolutely wonderful..My husband and daughter noticed a big difference also. They get home…the house is clean…dinner is cooked..mom is not laying on the couch. I can say that it changed my whole life. I still thank my sister when she calls me for letting me know about it.

Here is a site with new info on Procarin: http://www.customrxshoppe.com/compounding/prokarin/prokarin-testimonials/

[DrKalraMD]

Hi, research and trials on prokarin are still on, but till date its significant role in Multiple sclerosis is not well documented and established.
Websites on Prokarin:
http://www.edmsllc.com Prokarin research archive and resource site.
http://www.nationalmssociety.org/ctn/includes/getdocument.asp?c=132&s=news_file Article on clinical trial of Prokarin to treat MS fatigue by the National MS Society

“The National MS Society (NMSS) published a Research/Clinical Update on January 30, 2002 regarding the Prokarin study. The NMSS states in its conclusion that "As with any proposed treatment for any disease, well-designed clinical trials are essential to evaluate their potential benefit. Several issues with the design of the Prokarin study make it difficult to interpret, including the small sample size; the very different numbers of people in the treatment and placebo groups; potential confounding effects of caffeine, a known stimulant; and others." They felt that various aspects of the study rendered it insufficient to be firm scientific proof of the usefulness of Prokarin.

Various supporters of Prokarin, as well as the Prokarin Study statistician, Dr. Ray Smith, were quick to address these doubts about the quality of the study. Dr. Smith pointed out that the number of participants involved in the study was based on the large anticipated effect on fatigue that was noted in earlier studies. This very large effect size, known as the power of the study, was well above 80, which was more than sufficient to determine effect in a treatment group of 20 and a control group of 5.All studies follow the same formula to determine the number of participants necessary to give the study power (meaning the results will have statistical significance). The subjects were randomly selected from a basic patient pool into the two study groups so that variations in MS symptoms would not affect the outcomes. The issue of caffeine as a component of Prokarin was also addressed in the study: "The potential stimulant effect of caffeine needs to be considered, especially since the placebo did not contain caffeine. However, serum levels of caffeine were equal in the two groups, at least for the first 8 weeks of the trial, and the percentage of coffee drinkers in each group was high, and similar. Moreover, the caffeine level in the placebo group was higher at 12 weeks than in the Prokarin group, yet there was no concomitant increase in the placebo MFIS scores at 12 weeks (or the scores for other measures)."

Taken from website http://www.msakc.org/Articles/Prokarin.htm