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Heart Rhythm Community
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SNRI's and SSRI's and PVC onset
by notahypo, Sep 17, 2008 09:12PM
Hello Dr. Williams,
I am new to the forum and although I have many issues to inquire about, as a person, like many in this forum, has suffered from what "initally" began in 1992 at the age 38 was recurrent episodes of PSVT, and oddly enough then the onset of what seemed to be just unifocal -isolated PVC's that have appeared to progress to Multi-focal and Multi-form PVC's, a few years after they started in about 94/95' The PSVT episodes I used to get, would linger for many hours "sometimes" during an episode, which I later learned from my Cardiologist (that is them lasting so long) was from the alcohol I ingested several hours "prior" to an episode of PSVT. Now, I rarely get a breakthorugh episode hense the innitiation of a BB, Tenormin, in my case, and if I do get an break through episode, it subsides within minutes instead of hours. Of course, I attribute this reduction in frequency AND duration to both the BB and the discontinuation of being a former binge drinker BUT I have been abstinant from any alcohol use for several years now. Nevertheless, The PVC's , especially the intermitant very nasty runs that come and go, I know are here to stay and it took me many years to tolerate them, as I will never "totally" accept them, especially when they come in clusters or runs. I have been through the gamut of testing over these 15 years and through trial and error on many meds, for the anticipatory anxiety/panic associated with both "pre and post" episodes. After the sampling of the many MEDS. over the years, I settled on Tenormin and Klonopin ( mostly PRN now after the institute of an SSRI/SNRI ) again, after so many trials of different meds. Sorry, for such a long post but I wanted to clarify "my" specific conditions/symptoms, so I can maybe get some help/advice from others in this forum in the same horrific boat. I have tried many SSRI's and (now am on SNRI) and noted that some of them definately seem to aggravate or even possibly trigger my PVC' s. I was on cymbalta that seem to have NO effect on my heart rhythm but because of some other side-effects, I asked the doctor to try me on "effexor" ER. I took ONE tablet and the PVC's started a few hours later but I was in Bigeminy and Trigeminy and without a doubt in my mind, I am certain it was the effexor and NOT just a coincidence. If one has to be on an SSRI/SNRI (and god knows I tried them ALL) which one is LESS likely to affect the hearts conduction system? Does anyone know from their own experiance? Lastly even though I only took the one dose, my GP took me off and said he wanted to try a Brand New one on me called Prestiq (50mg) said it was similar to cymbalta yet I just read it was more similar to "effexor"! Yikes! I took my 1st dose earlier tonight NO unusual runs or PVC onset, YET? Can you advise on which SSRI/SNRI is best for anxiety/panic that is or may be less likely to induce or just even aggravate a so-called "benign" but 14 year rhythm disorder, especially PVC's, not so much a little tachycardia that some of these SSRI's are known to precipitate, as I am more bothered by the PVC's, as are most people that have them.
Thanks so much to ALL.
NotaHypo
I am new to the forum and although I have many issues to inquire about, as a person, like many in this forum, has suffered from what "initally" began in 1992 at the age 38 was recurrent episodes of PSVT, and oddly enough then the onset of what seemed to be just unifocal -isolated PVC's that have appeared to progress to Multi-focal and Multi-form PVC's, a few years after they started in about 94/95' The PSVT episodes I used to get, would linger for many hours "sometimes" during an episode, which I later learned from my Cardiologist (that is them lasting so long) was from the alcohol I ingested several hours "prior" to an episode of PSVT. Now, I rarely get a breakthorugh episode hense the innitiation of a BB, Tenormin, in my case, and if I do get an break through episode, it subsides within minutes instead of hours. Of course, I attribute this reduction in frequency AND duration to both the BB and the discontinuation of being a former binge drinker BUT I have been abstinant from any alcohol use for several years now. Nevertheless, The PVC's , especially the intermitant very nasty runs that come and go, I know are here to stay and it took me many years to tolerate them, as I will never "totally" accept them, especially when they come in clusters or runs. I have been through the gamut of testing over these 15 years and through trial and error on many meds, for the anticipatory anxiety/panic associated with both "pre and post" episodes. After the sampling of the many MEDS. over the years, I settled on Tenormin and Klonopin ( mostly PRN now after the institute of an SSRI/SNRI ) again, after so many trials of different meds. Sorry, for such a long post but I wanted to clarify "my" specific conditions/symptoms, so I can maybe get some help/advice from others in this forum in the same horrific boat. I have tried many SSRI's and (now am on SNRI) and noted that some of them definately seem to aggravate or even possibly trigger my PVC' s. I was on cymbalta that seem to have NO effect on my heart rhythm but because of some other side-effects, I asked the doctor to try me on "effexor" ER. I took ONE tablet and the PVC's started a few hours later but I was in Bigeminy and Trigeminy and without a doubt in my mind, I am certain it was the effexor and NOT just a coincidence. If one has to be on an SSRI/SNRI (and god knows I tried them ALL) which one is LESS likely to affect the hearts conduction system? Does anyone know from their own experiance? Lastly even though I only took the one dose, my GP took me off and said he wanted to try a Brand New one on me called Prestiq (50mg) said it was similar to cymbalta yet I just read it was more similar to "effexor"! Yikes! I took my 1st dose earlier tonight NO unusual runs or PVC onset, YET? Can you advise on which SSRI/SNRI is best for anxiety/panic that is or may be less likely to induce or just even aggravate a so-called "benign" but 14 year rhythm disorder, especially PVC's, not so much a little tachycardia that some of these SSRI's are known to precipitate, as I am more bothered by the PVC's, as are most people that have them.
Thanks so much to ALL.
NotaHypo
Member Comments (1)
by russsue, Sep 17, 2008 09:35PM
To: NotaHypo
Great question, I take Paxil CR 25 MG and have some of the same problems as you, I was just DX with SVT's. Cant wait to read the answer to your quetions.
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