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Hepatitis C Community
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Conflicting information on response rates to interferon and genotype 1a
by boater, Jan 27, 2002 12:00AM
This is a popular site(below):Does anyone know the correct answer? Is there a GENOTYPE 1 vs.1a ?
http://members.bellatlantic.net/~clotho/cfaq.htm#II.1.2a
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II.1.2a WHAT IS A GENOTYPE?
A genotype is the “family” to which our specific virus belongs. Our genotype does not change, but we can be re-infected with a different genotype. The most common genotypes are as follows: 1a, 1b, 1c, 2a, 2b, 2c, 3a, 3b, 4, 5 and 3a has the highest response rate to interferon, and people with this genotype are generally younger in age and usually IV drug users.
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III.1.1a INTERFERON ALPHA 2B, RECOMBINANT (INTRON A)
(last paragraph)
Factors most closely associated with response to interferon are: 1) absence of fibrosis or cirrhosis in the pretreatment liver biopsy; 2) HCV genotype other than 1; 3) lower RNA levels in the blood (e.g., less than 2 million/ml); and 4) shorter duration of infection (which often isn’t known).
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????????????????????
http://members.bellatlantic.net/~clotho/cfaq.htm#II.1.2a
---
II.1.2a WHAT IS A GENOTYPE?
A genotype is the “family” to which our specific virus belongs. Our genotype does not change, but we can be re-infected with a different genotype. The most common genotypes are as follows: 1a, 1b, 1c, 2a, 2b, 2c, 3a, 3b, 4, 5 and 3a has the highest response rate to interferon, and people with this genotype are generally younger in age and usually IV drug users.
---
III.1.1a INTERFERON ALPHA 2B, RECOMBINANT (INTRON A)
(last paragraph)
Factors most closely associated with response to interferon are: 1) absence of fibrosis or cirrhosis in the pretreatment liver biopsy; 2) HCV genotype other than 1; 3) lower RNA levels in the blood (e.g., less than 2 million/ml); and 4) shorter duration of infection (which often isn’t known).
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????????????????????
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