Oxymetazoline is a decongestant. It works by constricting (shrinking) blood vessels
(veins and arteries) in your body. The nasal formulation acts directly on the blood vessels in your
nasal tissues. Constriction of the blood vessels in your nose and sinuses leads to drainage of these
areas and a decrease in congestion.
Oxymetazoline nasal is used to treat congestion associated with allergies, hay fever, sinus
irritation, and the common cold.
Oxymetazoline nasal may also be used for purposes other than those listed in this
medication guide.