Uses: Metoclopramide injection is used to prevent nausea and vomiting from surgery or cancer chemotherapy. Metoclopramide is used to treat certain conditions of the stomach and intestines. Metoclopramide is used in diabetic patients who have poor emptying of their stomachs (gastroparesis). Treating gastroparesis can decrease symptoms of nausea, vomiting, and stomach/abdominal fullness. Metoclopramide is used as a short-term treatment (4 to 12 weeks). The injectable form of this medication should only be used when you cannot take the medication by mouth. Your doctor will switch you to the form taken by mouth as soon as you are able to take it. Metoclopramide works by blocking a natural substance (dopamine). It speeds up stomach emptying and movement of the upper intestines.