Chlorpheniramine is an antihistamine that reduces the natural chemical histamine in the body.
Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.
Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood
vessels can cause nasal congestion (stuffy nose).
The combination of chlorpheniramine and phenylephrine is used to treat symptoms of the
common cold or seasonal allergies, including sneezing, runny or stuffy nose, and itchy, watery eyes.
Chlorpheniramine and phenylephrine may also be used for other purposes not listed in this
medication guide.