Chlorpheniramine is an antihistamine. It blocks the effects of the naturally occurring
chemical histamine in the body. Chlorpheniramine prevents sneezing; itchy, watery eyes and
nose; and other symptoms of allergies and hay fever.
Dextromethorphan is a cough suppressant. It suppresses an area in the brain that causes
coughing.
Phenylpropanolamine is a decongestant. It constricts (shrinks) blood vessels (veins and
arteries). This reduces the blood flow and allows nasal and respiratory (breathing) passages to
open up.
Chlorpheniramine/dextromethorphan/phenylpropanolamine is used to treat nasal
congestion, sinusitis (inflammation of the sinuses), and coughs associated with allergies, hay
fever, and the common cold.
Phenylpropanolamine, an ingredient in this product, has been associated with an increased
risk of hemorrhagic stroke (bleeding into the brain or into tissue surrounding the brain) in
women. Men may also be at risk. Although the risk of hemorrhagic stroke is low, the U.S. Food
and Drug Administration (FDA) recommends that consumers not use any products that contain
phenylpropanolamine.
Chlorpheniramine/dextromethorphan/phenylpropanolamine may also be used for
purposes other than those listed in this medication guide.