Chlorpheniramine is an antihistamine that reduces the natural chemical histamine in the
body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.
Dextromethorphan is a cough suppressant. It affects the signals in the brain that trigger
cough reflex.
Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated
blood vessels can cause nasal congestion (stuffy nose).
Chlorpheniramine, dextromethorphan, and phenylephrine is used to treat sneezing, cough,
runny or stuffy nose, itchy or watery eyes, hives, skin rash, itching, and other symptoms of
allergies and the common cold.
Dextromethorphan will not treat a cough that is caused by smoking, asthma, or
emphysema.
Chlorpheniramine, dextromethorphan, and phenylephrine may also be used for other
purposes not listed in this medication guide.