guaifenesin/phenylephrine/PPA
Information, Symptoms, Treatments and Resources
What is guaifenesin/phenylephrine/PPA?
Generic Name: guaifenesin/phenylephrine/PPA
Guaifenesin is an expectorant. It is used to break up congestion and mucous to ease
breathing. Guaifenesin thins mucous, increases lubrication of the respiratory tract (lungs, nose,
and throat), and increases the removal of mucous.
Phenylpropanolamine and phenylephrine are decongestants. They constrict (shrink) blood
vessels (veins and arteries), which reduces the swelling of mucous membranes in areas such as
the nose and sinuses.
Guaifenesin/phenylephrine/phenylpropanolamine is used to treat the symptoms of the
common cold and of infections of your sinuses, your lungs, and your throat.
Phenylpropanolamine, an ingredient in this product, has been associated with an increased
risk of hemorrhagic stroke (bleeding into the brain or into tissue surrounding the brain) in
women. Men may also be at risk. Although the risk of hemorrhagic stroke is low, the U.S. Food
and Drug Administration (FDA) recommends that consumers not use any products that contain
phenylpropanolamine.
Guaifenesin/phenylephrine/phenylpropanolamine may also be used for purposes other
than those listed in this medication guide.
