Diclofenac is in a group of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). It
works by reducing hormones that cause inflammation and pain in the body.
Misoprostol reduces stomach acid and replaces protective substances in the stomach that are
reduced by NSAIDs.
The combination of diclofenac and misoprostol is used to treat osteoarthritis and rheumatoid
arthritis in people at high risk for developing stomach or intestinal ulcers.
Diclofenac and misoprostol may also be used for other purposes not listed in this medication
guide.