Diphenhydramine is an antihistamine. It blocks the effects of the naturally occurring chemical
histamine in the body and reduces congestion.
Hydrocodone is a narcotic. It is a pain reliever and a cough suppressant.
Phenylephrine is a decongestant. It works by constricting (shrinking) blood vessels (veins and
arteries) in the body. Constriction of blood vessels in the sinuses and nose decreases congestion.
Diphenhydramine, hydrocodone, and phenylephrine is used to treat cough and nasal congestion
associated with upper respiratory tract infections and allergies.
Diphenhydramine, hydrocodone, and phenylephrine may also be used for purposes other than
those listed in this medication guide.