Uses: This medication is used to treat various conditions such as allergic disorders; arthritis; blood diseases; breathing problems; certain cancers; eye diseases; intestinal disorders; collagen and skin diseases. It decreases your body's immune response to these diseases and reduces symptoms such as swelling and redness. Methylprednisolone is a corticosteroid hormone (glucocorticoid). This drug may also be used with other medications as a replacement for certain hormones.