Uses: Abacavir is used with other medications to help control your HIV infection, thereby improving your quality of life. It may also lower your risk of complications from HIV (such as new infections, cancers). Abacavir belongs to a class of drugs known as nucleoside reverse transcriptase inhibitors-NRTI. Abacavir is not a cure for HIV infection, and it does not prevent the spread of HIV to others through sexual contact or blood contamination (such as sharing used needles).