Alosetron blocks the action of a chemical called serotonin in the intestines. This slows the
movement of stools (bowel movements) through the intestines.
Alosetron is used to treat severe, chronic irritable bowel syndrome (IBS) in women who
have had diarrhea as the main symptom for at least 6 months. Alosetron should be used only in
women who have tried other IBS treatments without success. Alosetron has not been shown to
be effective in men with IBS.
Alosetron should be prescribed only by a qualified doctor who is enrolled in a prescribing
program specific for this drug. You will be required to read and sign a Patient-Physician
Agreement form before you get a prescription for alosetron.
Alosetron may also be used for other purposes not listed in this medication guide.