Uses: Cilostazol is used to improve the symptoms of a certain blood flow problem in the legs (intermittent claudication). Cilostazol can decrease the muscle pain/cramps that occur during exercise/walking. Claudication pain is caused by too little oxygen getting to the muscles. Cilostazol can increase blood flow and the amount of oxygen that gets to the muscles. Cilostazol is an "anti-platelet" and a vasodilator. It works by preventing certain blood cells (platelets) from sticking together and by widening blood vessels in the legs. This helps the blood to move more easily and increases blood flow.