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GNC Accused of Selling Supplements with Unlawful Ingredients

Oct 30, 2015 - 3 comments

GNC Accused of Selling Supplements with Unlawful Ingredients

(Date Posted: 10/28/2015)
On October 22, 2015, Oregon Attorney General Ellen Rosenblum filed a lawsuit against supplement retailer GNC, alleging that the company sold products that were adulterated with BMPEA and picamilon, which are not lawful dietary supplement ingredients. The lawsuit states that GNC "knew or should have known" the products contained these unlawful ingredients.

BMPEA (beta- methylphenylethylamine) is a synthetic, amphetamine-like compound found in some weight loss and workout supplements. It is often found in supplements labeled as containing acacia rigidula, although it does not appear to be a component of this plant. It is not a legal dietary supplement ingredient. The Attorney General's lawsuit contends GNC should have known as early as 2013 that BMPEA was not a lawful dietary ingredient but continued selling products containing BMPEA until April 2015, when the FDA formally announced it did not meet the definition of a dietary ingredient and issued warning letters to a number of supplement manufacturers. Products containing BMPEA sold by GNC include Fastin and Fastin DMAA Free (Hi Tech Pharmaceuticals), Meltdown (VPX Sports) and Isolean 2 (Advanced Nutrition Systems).

Picamilon is a synthetic compound of GABA and niacin found in some supplements promoted for physical performance or cognitive enhancement. According to the lawsuit, GNC was aware as early as May of 2007 that it was not a lawful dietary supplement ingredient, but sold products containing the compound, such as Charge Extreme Energy Booster (Labrada Bodybuilding Nutrition), Turbo Shred (Swole Sports Nutrition) and Mr. Hyde - Fruit Punch (Prosupps USA LLC) until September of 2015.

GNC has filed a motion to remove the lawsuit. A statement issued by the company noted," There is no basis for the Oregon Attorney General's assertion that GNC or any other retailer "knew or should have known" that these ingredients were not legal for use in dietary supplements. As a matter of law, this critical legal issue remains undetermined as neither FDA nor any court has issued a legally binding determination of the status of these ingredients. GNC stopped selling products with BMPEA and picamilon, immediately upon learning indirectly, rather than from notice directed at GNC, that FDA did not view BMPEA and picamilon as legal dietary ingredients."

See Related Warnings:

FDA Identifies More Products Listing Synthetic Amphetamine

Does Your Weight Loss or Sports Supplement Contain Synthetic Amphetamine?

Study Finds Some Vinpocetine Supplements Contain No Vinpocetine

To read the complaint filed against GNC, which includes a list of products containing BMPEA and picamilon which were sold by the company, use the red link below.

green tomatoes and apple peels for bigger, stronger muscles

Oct 29, 2015 - 0 comments

Using a screening method that previously identified a compound in apple peel as a muscle-boosting agent, a team of University of Iowa scientists has now discovered that tomatidine, a compound from green tomatoes, is even more potent for building muscle and protecting against muscle atrophy.

Muscle atrophy, or wasting, is caused by aging and a variety of illnesses and injuries, including cancer, heart failure, and orthopedic injuries, to name a few. It makes people weak and fatigued, impairs physical activity and quality of life, and predisposes people to falls and fractures. The condition affects more than 50 million Americans annually, including 30 million people over age 60, and often forces people into nursing homes or rehabilitation facilities.

"Muscle atrophy causes many problems for people, their families, and the health care system in general," says Christopher Adams, M.D., Ph.D., UI associate professor of internal medicine and molecular physiology and biophysics. "However, we lack an effective way to prevent or treat it. Exercise certainly helps, but it's not enough and not very possible for many people who are ill or injured."

More muscle, less fat

In a new study, published online April 9 in the Journal of Biological Chemistry, Adams searched for a small molecule compound that might be used to treat muscle atrophy. He zeroed in on tomatidine using a systems biology tool called the Connectivity Map, which was developed at the Broad Institute of MIT and Harvard University. Adams discovered that tomatidine generates changes in gene expression that are essentially opposite to the changes that occur in muscle cells when people are affected by muscle atrophy.

After identifying tomatidine, Adams and his team tested its effects on skeletal muscle. They first discovered that tomatidine stimulates growth of cultured muscle cells from humans.

"That result was important because we are looking for something that can help people," Adams says.

Their next step was to add tomatidine to the diet of mice. They found that healthy mice supplemented with tomatidine grew bigger muscles, became stronger and could exercise longer. And, most importantly, they found that tomatidine prevented and treated muscle atrophy.

Interestingly, although mice fed tomatidine had larger muscles, their overall body weight did not change due to a corresponding loss of fat, suggesting that the compound may also have potential for treating obesity.

Designing healthier foods

An attractive aspect of tomatidine is that it is a natural compound derived from tomatoes. It is produced when alpha-tomatine, which is found in tomato plants and in green tomatoes in particular, is digested in the gut.

"Green tomatoes are safe to eat in moderation. But we don't know how many green tomatoes a person would need to eat to get a dose of tomatidine similar to what we gave the mice. We also don't know if such a dose of tomatidine will be safe for people, or if it will have the same effect in people as it does in mice," Adams says. "We are working hard to answer these questions, hoping to find relatively simple ways that people can maintain muscle mass and function, or if necessary, regain it."

Adams and his team previously used this same research strategy to discover that ursolic acid, a compound from apple peels, promotes muscle growth.

"Tomatidine is significantly more potent than ursolic acid and appears to have a different mechanism of action. This is a step in the right direction," Adams says. "We are now very interested in the possibility that several food-based natural compounds such as tomatidine and ursolic acid might someday be combined into science-based supplements, or even simply incorporated into everyday foods to make them healthier."

In an effort to accelerate this research and translate it to people, Adams and his colleagues have founded a biotech company called Emmyon. The company recently received funding from the National Institutes of Health to develop strategies for preserving muscle mass and function during the aging process. The company is also using tomatidine and ursolic acid as natural leads for new medicines targeting muscle atrophy and obesity.

Story Source:

The above post is reprinted from materials provided by University of Iowa. The original item was written by Jennifer Brown.

5 Metabolism Death Foods

Oct 26, 2015 - 10 comments

Metabolism Death Foods
It’s really unsatisfying to stick to an exercise program, make the right diet changes, and still not see the results you want to see. Has that ever been you? It can be really frustrating.
The reason this can happen is even though you think you’re consuming a healthy food , you might have some hidden food in your diet that is ruining your weight loss efforts.

The foods that keep you from losing the last 10 pounds and keep you stuck at a plateau are what I call the metabolism death foods! The term may sound scary, and it can be. And the craziest thing about these foods is that they are often labeled as “health foods”.

Here are the five metabolism death foods you need to switch out of your diet to take your metabolism and fat burning potential to the next level!

Metabolism Death Foods
There are five main foods that can absolutely ruin your weight loss efforts. I call these the metabolism death foods. You will want to remove and replace these foods with healthy alternatives if you want to see quick results.

1. Fruit Juice - Contrary to popular belief, fat isn’t the first thing that will make you fat, it’s consuming too much sugar. Drinking fruit juice and consuming too much sugar will absolutely wreck your metabolism!

Fruit juice – including most apple, orange and grape juice – is basically chemically laden sugar water! I know something like apple juice sounds healthy, but some manufacturers turn apples into juice by adding in sugar, food coloring and flavorings. That is the apple juice you buy today.

One 8-ounce glass of fruit juice contains 30 grams of sugar where a soda contains 28 grams of sugar!

Also, you should avoid other forms of sugar, which can hide under names like: corn syrup, dextrose, fructose, juice concentrate, maltodextrin, raw sugar and brown sugar.

What to do instead: To replace fruit juice I recommend making homemade lemonade mixing real lemon juice, water and stevia. Kombucha is another great option as (nature’s sports drink!) is another great option!

2. Whole Grains - Whole grains may be the #1 offender when it comes to ruining your metabolism and weight loss efforts. I know it may seem like “whole grains” like wheat bread are healthy but most are far from helping your metabolism.

Three of the main compounds in grains hurt your metabolism include gluten, starch and phytic acid. Gluten can cause inflammation, starch turns into sugar quickly and phytic acid binds to minerals so you’re not getting most of the minerals and vitamins from whole grains that could have helped your metabolism.

What to do instead: A better option for fat loss is replacing your daily intake of grains with fruits and vegetables or consuming up to one piece daily of a sprouted grain bread or sourdough. Also, the best flour replacement to use instead of wheat flour is coconut flour. Coconut flour is a dieters best friend because it’s high in fiber which supports rapid fat loss and contains fats your body can burn as fuel.

3. Canola Oil - Using the wrong type of oil can keep you from losing that last 10 pounds and put a halt to any results you might see. Canola oil contains hydrogenated oils which may cause inflammation throughout the entire body disrupting your hormones and metabolism.

What to do instead: Replace all vegetables oils with coconut oil and grass-fed butter to boost your metabolism. I always say, butter is your belly’s best friend. Grass-fed butter supports metabolism because it is high in CLA and coconut oil supports fat loss because it’s high in MCFA’s.

4. Peanut Butter - Yes, peanut butter is tasty, but it can also ruin your gut health. Peanuts are grown on the soil and stored moist in silos which then cause them to grow a type of fungus called aflatoxins which can effect the health of your gut.

Peanuts are one of the most common allergens today and have been linked to food sensitivities, leaky gut and a slow metabolism. Also, peanuts are very high in omega-6 fatty acids which may cause serious inflammation in the body. For these many reasons, peanut butter is a metabolism death food!

What to do instead: If you want to start revving up your metabolism then make a switch to almond butter. Almonds are high in an amino acid L-arginine which increases HGH production in your body. This is turn causes your body to build lean muscle which sends your metabolism sky high!

Just one tablespoon spoon of almond butter with celery, in a smoothie or with some apples are great snacks to re-ignite your metabolism.

5. Granola - This “health food” has had a health halo around it for years but it’s secretly been hiding as a wolf in sheep’s clothing that kills your metabolism.

Today’s granola has many issues in that it’s made up of whole grains and sugar. Now what’s most surprising about granola is that the processed honey in it is a major cause of weight gain. A study at Texas A&M University tested honey and found 76% of it contained no pollen whatsoever and it had been high temperature pasteurized so it is no better than corn syrup!

What to do instead: A great replacement to store bough granola is to make homemade sprouted granola. Simply soak almonds, pecans, cashews and chia seeds in water for eight hours then set them out for a day on a paper towel. Then mix these ingredients with raw local honey, raisins, coconut flakes, cinnamon and sea salt. Place them in a dehydrator or oven and you have a great tasting metabolism boosting snack.
Source: Dr. Axe

Central line-associated bloodstream infections

Oct 17, 2015 - 0 comments

Central line-associated bloodstream infections (CLABSI) are the most common cause of health care-associated infections of the bloodstream. A single incident of CLABSI can add $56,000 to your hospital tab — although you might not live long enough to see the bill.

Between 12 and 25 percent of patients who acquire CLABSI never make it out of the hospital. Each year 250,000 central lines become infected, accounting for an estimated 62,000 hospital deaths in the US.