Grapefruit can interact with at least 85 different prescription drugs, increasing their concentration in blood, causing the potential for an overdose
This is really great info, Rosy. Many yrs back I did a "grapefruit diet"....and as I got older I began reading about interactions with SO MANY Rx meds.....as much as my hubby and I LOVE pink grapefruit and juice as well....we just surrendered and gave it up to be safe. There are warnings on the fact sheets from the Pharmacy....but not everybody reads those....so, we just decided to SIMPLIFY....and not partake :)
FYI, the reason grapefruit juice interacts with so many meds is because it metabolizes in the liver through a common pathway, the cytochrome p450 enzyme system. When two or more drugs are used, they are not able to metabolize all of the drugs competing for the same pathway. Therefore, one or more if the drugs build up in the system.
It is known that many addicts will try adding grapefruit juice while taking their pain meds. Therefore they have more free drug available. I personally think the effect is negligible. The warning really applies to individuals who drink tons of grapefruit juice everyday. The occasional glass should not have any impact..
Yes this is something I heard for Years when passing out meds. I like my Grapefruit and now I can eat all I want. Good Job on doing your homework Girl. You just Rock on my Dear Friend..Keep up that nice since of humor too!! I love you for who you are and have since day one when I named you..OOPS that was no big deal..just slipped out but I still love you..lol
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