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Acronyms, Abbreviations, and Definitions:  Hepatitis C

Dec 04, 2011 - 2 comments
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Below is a list of acronyms, abbreviations, and definitions frequently used in discussions regarding Hepatitis C and treatment.  Thank you to hrsepwrguy for sharing the link to this list.  
Advocate1955

Hepatitis C Acronyms/Abbreviations/Definitions
  
HCV - Hep C : Hepatitis C virus
Boceprevir: Victrelis
Teleprevir: Incevik
Inf: Interferon
Riba/Rbv: Ribavirin
Bx: Biopsy : Invasive liver sample removed and analized to determine liver condition
Fibroscan: Non invasive Ultrasound Technique for determining liver condition
Fibrosure/Fibrotest: Combination of blood test scores used for determining liver condition
Dx: Diagnosis
GT: Genotype
IR: Insulin Resistant
IL28B: A gene polymorphism which helps in Tx prediction -  CC , CT , TT
Sx: Side effects
Tx : Treatment
SOT: Start of Treatment
EOT: End of Treatment
RVR: Rapid viral response - Undetected virus at 4 wks. Tx
cEVR: Complete Early Viral Response: PCR Und at Week 12 (P/R Tx)
EVR: Early Virological Response:  >2 Log Drop at Wk. 12
eRVR - Extended Rapid Viral Response - Und virus @ Wk.4 - Wk. 12
Und : Undetected virus
SVR: Sustained Viral Response: Und after 6 months EOT
P/R Tx: Pegelated Interferon / Ribaviron Treatment (old term - SOC: standard of care)
VL: Viral Load - amount of virons per IU (International Unit)
IU: International Unit (1 IU = 2.5 VL Copies apx )
HVL: High Viral Load (≥800,000 IU)
LVL: Low viral load (<800,000IU
PCR: Polymerase Chain Reaction
RT-PCR quantitative: using Reverse Transcription-Polymerase Chain Reaction- to count how many virus are in blood

RT-PCR qualitative: a "positive" or "negative" using Reverse
Transcription-Polymerase Chain Reaction to see if there are at least 50 IU/mlviruses detected in bloodRNA: RiboNucleic Acid
Rx: Prescription
TMA: Transcription Mediated Amplification
All oral Tx: Interferon-free treatment (Phase 2 Clinical Trials)
AFP: Alpha-FetoProtein
ALP: Alkaline Phosphatase (Alk Phos)
ALT/SGPT: Alanine Aminotransferase - liver function blood test
AST/SGOT: Aspartate Aminotransferase - liver function blood test
CBC: Complete Blood Count
DAA: Direct Acting Anti-viral
ELISA: Enzyme-Linked ImmunoSorbent Assay
EPO: Erythropoietin Epoetin alfa (Epogen/Procrit), Darbepoetin alfa (Aranesp)
ESA:: Erythropoiesis Stimulating Agent
ESLD: End-Stage Liver Disease
GGT:: Gamma Glutamyl Transpeptidase
HCC: HepatoCellular Carcinoma (Liver Cancer)
HDL: High Density Lipoproteins (Good Cholesterol)
HGB: Hemoglobin
IFN: Interferon (Alpha 2a/2b)
IU: International Unit 1 IU (2.5 VL Copies apx)
LDL: Low Density Lipoproteins (Bad Cholesterol)
LFT: Liver Function Test
LLN: Lower Limit of Normal
NAFLD: Non Alcoholic Fatty Liver Disease (Steatosis)
NASH: Non Alcoholic SteatoHepatitis
Neup: Neupogen
PEG: PolyEthylene Glycol
PegIFN: Pegylated Interferon Alpha (2a/2b)
PI : Protease Inhibitor
RBC: Red Blood Cell Count
RIBA: Recombinant ImmunoBlot Assay
TMA: Transcription Mediated Amplification
TSH: Thyroid stimulating hormone or Thyrotropin
ULN: Upper Limit of Normal
VLDL: Very Low Density Lipoproteins
WBC: White Blood Cell Count


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1833444_tn?1325560662
by ceecee444, Dec 04, 2011
Thanks for this post ...I sometimes felt stupid when reading some post and racking my brain on what that meant I copied and pasted this to my journal, so now I am informed :-)

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by christinaf28, Dec 09, 2011
me too thank you so much !!!!

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