Targeted drug therapy, including chemotherapy drugs like bevacizumab (Avastin), cetuximab (Erbitux) and panitumumab (Vectibix) can help if surgery isn't an option. These drugs have varied success, and come with the typical side effects of cancer drugs, from nausea, diarrhea and abdominal pain to stroke or heart attack symptoms. You and your doctor will carefully weigh the risks and potential benefits before starting a drug regimen