Information, Symptoms, Treatments and Resources

Phenergan Rect | Phenergan Inj | Phenergan Oral


Common Brand Name(s): Phen-Tuss, Phenergan
Phonetic Pronunciation: (pro-METH-uh-zeen)
Information last revised May 2010

What does PROMETHAZINE-ORAL look like?

Hit08010promethazine 6.25 mg/5 mL Syrup
Zyd00420promethazine 50 mg Tab
Glb10410promethazine 25 mg Tab
Abe04050promethazine 12.5 mg Tab
Mkr20420promethazine 50 mg Tab
Glb10420promethazine 50 mg Tab
Zyp00410promethazine 25 mg Tab
Qlt54370promethazine 12.5 mg Tab
Sun01460promethazine 6.25 mg/5 mL Syrup
Zyd00400promethazine 12.5 mg Tab
Glb10400promethazine 12.5 mg Tab


Promethazine is used to prevent and treat nausea and vomiting related to certain conditions (e.g., motion sickness, before/after surgery). It is also used to treat allergic symptoms such as rash, itching, and runny nose. It may be used for a short time to treat a runny nose due to the common cold. It may also be used to help you feel calmer before/after surgery or to help certain narcotic pain relievers (e.g., meperidine) work better. Promethazine is an antihistamine. It works by blocking a certain natural substance (histamine) that your body makes during an allergic reaction. Its other effects (e.g., anti-nausea, calming, pain relief) may work by affecting other natural substances (e.g., acetylcholine) and by acting directly on certain parts of the brain. Cough-and-cold products have not been shown to be safe or effective in children younger than 6 years. Therefore, do not use this product to treat cold symptoms in children younger than 6 years unless specifically directed by the doctor. Some products (such as long-acting tablets/capsules) are not recommended for use in children younger than 12 years. Ask your doctor or pharmacist for more details about using your product safely. These products do not cure or shorten the length of the common cold and may cause serious side effects. To decrease the risk for serious side effects, carefully follow all dosage directions. Do not use this product to make a child sleepy. Do not give other cough-and-cold medication that might contain the same or similar ingredients (see also Drug Interactions section). Ask the doctor or pharmacist about other ways to relieve cough and cold symptoms (such as drinking enough fluids, using a humidifier or saline nose drops/spray).
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This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
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