Common Brand Name(s): Creon, Pancrease, Protilase, Ultrase, Zenpep, Zymase
Phonetic Pronunciation: (pan-kreh-LIP-aze)
Information last revised August 2010
What does PANCRELIPASE EC CAP -ORAL look like?
Pancrease MT 4 4,000-12,000-12,000 unit Cap
Ultrase MT 12 223 mg (12,000-39K-39K unit) Cap
Pancrease MT 20 20,000-44,000-56,000 unit Cap
Pangestyme EC 4,500-25,000-20,000 unit Cap
Pangestyme CN 10 10,000-37,500-33,200 unit Cap
Lipram-PN20 20,000-44,000-56,000 unit Cap
Panocaps MT 16 16,000-48,000-48,000 unit Cap
Creon 12,000-38,000-60,000 unit Cap
Zenpep 20,000-68,000-109,000 unit Cap
Pancrease MT 10 10,000-30,000-30,000 unit Cap
Ultrase MT 20 371 mg (20,000-65K-65K unit) Cap
Creon 20 497 mg(20,000-75K-66.4K unit) Cap
Pangestyme MT 16 16,000-48,000-48,000 unit Cap
Lipram 4500 4,500-25,000-20,000 unit Cap
Pancrecarb MS-16 16,000-52,000-52,000 unit Cap
Panocaps 4,500-25,000-20,000 unit Cap
Creon 24,000-76,000-120,000 unit Cap
Zenpep 5,000-17,000-27,000 unit Cap
Pancrease MT 16 16,000-48,000-48,000 unit Cap
Ultrase MT 18 333 mg(18K-58.5K-58.5K unit) Cap
Creon 5 124 mg (5K-18.75K-16.6K unit) Cap
Pangestyme UL 18 18,000-58,500-58,500 unit Cap
Lipram-PN10 10,000-30,000-30,000 unit Cap
Ultracaps MT 20 20,000-65,000-65,000 unit Cap
Palcaps 10 10,000-37,500-33,200 unit Cap
Creon 6,000-19,000-30,000 unit Cap
Zenpep 10,000-34,000-55,000 unit Cap
Ultrase MT 12 223 mg (12,000-39K-39K unit) Cap
Creon 10 249 mg(10K-37.5K-33.2K unit) Cap
Pangestyme CN 20 20,000-75,000-66,400 unit Cap
Pangestyme UL 20 20,000-65,000-65,000 unit Cap
Lipram-PN16 16,000-48,000-48,000 unit Cap
Panocaps MT 20 20,000-44,000-56,000 unit Cap
Pancrelipase 4500 4,500-25,000-20,000 unit Cap
Zenpep 15,000-51,000-82,000 unit Cap
Pancrelipase 5000 5,000-17,000-27,000 unit Cap
This medication contains digestive enzymes to help break down and digest fats, starch, and proteins in food. It is used in conditions where the pancreas cannot make or does not release enough digestive enzymes into the small intestines to digest the food (e.g., chronic pancreatitis, cystic fibrosis, cancer of the pancreas, post-pancreatectomy, post-gastrointestinal bypass surgery).
If you miss a dose, take the next dose with your next meal or snack as directed. Do not double the dose to catch up.
How To Use
Some brands of this medication have a Medication Guide provided by your pharmacist. If one is available, read the Medication Guide before your start taking this medication and each time you get a refill. If you have any questions, consult your doctor or pharmacist. Take this medication by mouth with meals and snacks as directed by your doctor. Swallow the capsule whole. Do not crush or chew the capsules or keep the capsules in your mouth. Doing so can irritate the mouth and also change the way the medication works. If swallowing is difficult, then the capsule may be opened and the contents mixed in a small amount of liquid or soft food that does not need to be chewed (such as room-temperature applesauce). Do not mix the contents of the capsule with alkaline food or liquid (such as milk, ice cream, tea). Consult your doctor or pharmacist for more information about what foods/liquids to avoid when mixing. Swallow the food or liquid right away, making sure not to chew the medication. Drink a glass of water or juice after swallowing the food to make sure all the medication is swallowed. Do not save the medication mixture for later. Dosage is based on your medical condition, diet, and response to therapy. Drink plenty of fluids while taking this medication unless your doctor tells you otherwise. Use this medication regularly to get the most benefit from it. Take it with every meal or snack. If your doctor has recommended that you follow a special diet, it is very important to follow the diet to get the most benefit from this medication. Do not change brands or dosage forms of pancrelipase without consulting your doctor or pharmacist. Different products may contain different amounts of the digestive enzymes. Inform your doctor if your condition persists or worsens.
Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first. This drug should not be used with the following medications because very serious interactions may occur: acarbose, miglitol. If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting pancrelipase. Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use. This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.
Do not share this product with others.
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center.
Before taking pancrelipase, tell your doctor or pharmacist if you are allergic to it; or to pork protein; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: sudden/severe swelling of the pancreas (acute pancreatitis), sudden worsening of long-term disease of the pancreas. Before using this medication, tell your doctor or pharmacist your medical history. During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.
Store at room temperature away from light and moisture. Check the product package for more details on how to store your brand, or ask your pharmacist. Do not store in the bathroom. Keep all medicines away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.
Diarrhea, constipation, abdominal pain/cramps, nausea, or vomiting may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor immediately if any of these rare but very serious side effects occur: severe constipation, severe stomach/abdominal discomfort, frequent/painful urination, joint pain. A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
The information contained in the First DataBank databases is intended to supplement the knowledge of physicians, pharmacists, and other healthcare professionals regarding drug therapy problems and patient counselling information. This information is advisory only and is not intended to replace sound clinical judgment in the delivery of healthcare services. First DataBank disclaims all warranties, whether expressed or implied, including any warranty as to the quality, accuracy, and suitability of this information for any purpose.
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