PANTOPRAZOLE - INJECTION
Common Brand Name(s): Protonix IV
Phonetic Pronunciation: (pan-TOE-pruh-zole)
Information last revised November 2010
What does PANTOPRAZOLE - INJECTION look like?
Protonix 40 mg IV Solution
Protonix 40 mg IV Solution
Protonix 40 mg IV Solution
Uses:
Pantoprazole is a proton pump inhibitor (PPI) used to treat stomach and throat problems related to extra stomach acid (e.g., esophagitis, ulcers). Decreasing extra stomach acid can help relieve symptoms such as heartburn, difficulty swallowing, persistent cough, and trouble sleeping. It can also prevent serious problems caused by acid damage to your digestive system (e.g., ulcers, cancer of the esophagus). The injection form of this drug is used for a short time when you cannot take the medication by mouth. When possible, your doctor should switch you to the form that is taken by mouth. Pantoprazole works by blocking acid production in the stomach.
Missed Dose
If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
How To Use
This medication is given by injection into a vein by a health care professional. Health care professionals must follow all the manufacturer's instructions for properly mixing and giving this drug. If you have any questions about using this medication properly, consult your doctor or pharmacist. The dosage is based on your medical condition and response to treatment. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard needles and medical supplies safely. Consult your pharmacist. Tell your doctor if your condition persists or worsens.
Drug Interactions
Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first. This drug should not be used with the following medications because very serious interactions may occur: atazanavir, nelfinavir. If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting pantoprazole. Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: products that contain zinc (e.g., zinc supplements, vitamins that contain zinc), warfarin. Some products need stomach acid so that the body can absorb them properly (such as ampicillin, iron supplements, calcium supplements, dasatinib, azole antifungals including ketoconazole). Pantoprazole decreases stomach acid, so it may change how well these other products work. Before using pantoprazole, consult your doctor or pharmacist about the other medications you take and for advice on how to reduce or avoid these types of interactions. This product can affect the results of certain lab tests (e.g., urine screen for THC), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug. This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.
Notes
Do not share this medication with others. Laboratory and/or medical tests may be performed to monitor your progress. Consult your doctor for more information.
Overdose
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: loss of coordination, shakiness (tremor).
Precautions
Before using pantoprazole, tell your doctor or pharmacist if you are allergic to it; or to other proton pump inhibitors (e.g., lansoprazole, omeprazole); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: lack of certain minerals in the body (e.g., iron or zinc). Some symptoms may actually be signs of a more serious condition. Tell your doctor immediately if you have: heartburn with lightheadedness/sweating/dizziness, chest/jaw/left arm pain (especially with trouble breathing), unexplained weight loss. Proton pump inhibitors (such as pantoprazole) may increase your risk of bone fractures, especially with longer use, higher doses, and in older adults. Talk with your doctor about ways to prevent bone loss/fracture, such as taking calcium (such as calcium citrate) and vitamin D supplements. During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. This medication passes into breast milk. Consult your doctor before breast-feeding.
Storage
Store unmixed vials at room temperature between 68-77 degrees F (20-25 degrees C) away from light. Brief storage between 59-86 degrees F (15-30 degrees C) is permitted. Do not freeze. See package information for information on how to store this product after mixing. Keep all medicines away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.
Side Effects
Redness/pain/swelling at the injection site, headache, nausea, or diarrhea may occur. If any of these effects persist or worsen, tell your doctor promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. This medication may rarely increase the risk of a serious lung infection (e.g., pneumonia). Tell your doctor immediately if any of these symptoms of lung infection occur: difficult/painful breathing, cough, fever, unusual tiredness. A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
The information contained in the First DataBank databases is intended to supplement the knowledge of physicians, pharmacists, and other healthcare professionals regarding drug therapy problems and patient counselling information. This information is advisory only and is not intended to replace sound clinical judgment in the delivery of healthcare services. First DataBank disclaims all warranties, whether expressed or implied, including any warranty as to the quality, accuracy, and suitability of this information for any purpose.
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