Hi. I have taken Accutane twice as an adult. Side effects such as dryness of the vagina, eyes, noses etc should disappear within 5 weeks of stopping your medicine. This is because Accutane has a long half life and can stay in your body for 5 weeks afterwards.
Dryness and sensitivity of facial skin may continue for 6 months after stopping treatment as Accutane shrinks the sebaceous glands, and they grow back very slowly.
The side effects I had (such as muscle and joint paint) were tolerable and controllable with non-prescription pain killers.
Accutane is the medicine most likely to result in a long term remission from acne after a course lasting 16-24 weeks.