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Bupropion (Wellbutrin)

Does anyone have experience with taking Bupropion (Wellbutrin) to help with no longer using 30 mg Roxicet?
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4522800 tn?1470325834
Wellburtrin seems to be one of the AD meds Drs will prescribe after drug use too. It treats magor depressive disorders and seasonal affective disorders. The zyban of bupropin is to help stop smoking by reducing carvings. It takes a good month to 6 weeks for it to kick in.
Wellbutrin is a norepinephrine and dopamine reuptake inhibitor. It has potential to make you happy etc. It is unlikely to make you gain weight or affect your libido.
It also can be used with some serotonin reuptake inhibitors (SRI)
Bless
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5986700 tn?1380791380
Hi,
I have been taking wellbutrin for over ten years....love it and I can say
it certainly hasn't hurt throught any of the 100 times of tried to detox.
Helpful - 0
4113881 tn?1415850276
There was a clinical trial on whether or not Welbutrin helps with opioid withdrawal. The one thing I dont like about the study is that it was done on only 40 subjects. All the same, the evidence suggests that Bupropion doesn't help with opiod withdrawals however further trials are needed with a bigger class to support the evidence. I will post the abstract and link to the full study below.

Preliminary Study of Buprenorphine and Bupropion for Opioid Dependent Smokers

Abstract

In this double-blind, placebo-controlled trial, bupropion (BUPRO, 300 mg/day) was compared to placebo (PBO) for concurrent treatment of opioid and tobacco addiction in 40 opioid-dependent smokers stabilized on buprenorphine (BUPRE, 24 mg/day). Participants received contingent, monetary reinforcement for abstinence from smoking, illicit opioids, and cocaine. Significant differences in treatment retention were observed (BUPRE+BUPRO, 58%; BUPRE+PBO, 90%). BUPRO treatment was not more effective than placebo for abstinence from tobacco, opioids, or cocaine in BUPRE stabilized patients. These preliminary findings do not support the efficacy of BUPRO, in combination with BUPRE, for concurrent treatment of opioid and tobacco addiction.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2588345/
Helpful - 0
4113881 tn?1415850276
Where the study refers to BUPRO it is talking about Welbutrin whereas when it refers to BUPRE it is talking about Subs.
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