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5203459 tn?1373371504

Can you take 5THP & DLPA if you are on Effexor XR?

I've read that you cannot take this if you are on a SSRI, but Effexor XR is considered a SNRI. I just wanted to make sure before I start this regimine. Starting it to help come off of Tramadol. :(
9 Responses
480448 tn?1426952138
While it isn't as big an issue as with the SSRIs, most doctors and pharmacists would probably still caution against using them concurrently.  I would ask your doc or pharmacist.  Perhaps you would do okay with an Effexor increase?  How long have you been on it, and what dose do you take?
4810126 tn?1503946335
Hi & Welcome to the forum!

Here's a link of interactions w/ 5-HTP:
Hope this. Please keep posting. We're here.
5203459 tn?1373371504
I've been on the effexor xr about 2 years, I take 75mg.
5203459 tn?1373371504
I actually probably take it a day on day off. Because I've been on the tramadol, my depression/anxiety symptoms having been as bad. It would be nice if they prescribed Tramadol for depression!!! It would be perfect. :(
480448 tn?1426952138
Your symptoms have been bad probably BECAUSE you're taking both (tramadol and Effexor).  They basically act in very similar ways, and are both very "activating" which would make anxiety much higher.  Are you on the Effexor for primary depression, or an anxiety disorder?

I would recommend talking to your doctor on the best way to proceed before adding anything else to the mix.  Most likely, once you're off the tramadol and give yourself some time to readjust, you'll feel better.  At that point, you could discuss maybe increasing your Effexor dose.

I honestly think the best way to handle the emotional w/d coming off tramadol (or an opiate) is to not add too much else, and let the your brain get back into balance without adding more substances.  You're already on the Effexor, that will help to some degree.  Just remember, the emotional symptoms are normal, and they just take some time to resolve.

Good luck!
4810126 tn?1503946335
Before you get too enamored about Tramadol, there are quite a few people on this site who might tell you differently re: depression and their experiences on that tricky narcotic.
5203459 tn?1373371504
Thank you
nursegirl6572! These are the things I need to hear. The worst part is the lack of energy that I have coming off the tramadol.
And EvolverU, I am far from "enamored" with tramadol. It's been an addicting roller coaster for three years. I was just saying it has helped with my depression/lack of energy from depression, thus making it more addictive to me. It's funny how much it's helped vs. actual antidepressants.
I hear effexor is a pain in the *** to withdrawl from as well. I swear in a few years, they will approve tramadol for more than pain...
But NO I still want off of it. I do not want to be addicted to ANYTHING!
Avatar universal
This question is best to ask your doctir  that knows the interactions as well as the risk  dont take this into your own hands  talk with the doctor b/4 taking annything...................Gnarly
4810126 tn?1503946335
Please forgive me! I misunderstood about the Trams. Glad to hear you're determined to come off. Good for you!
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