Drug interraction between Methadone and Paxil

[Plumpkin]

I have been on Methadone maintenance for almost 3 years and have abstained from all other drugs and alcohol.  I have been experiencing feelings of depression and feeling overwhelmed and would like to try an anti-depressent.  I took Paxil, briefly while in College.  I had a good result and remember no sexual side effect.  Is there a negative reaction when Methadon and Paxil are mixed?  Will it show up on a drug screen?  If Paxil isn't an anti-depressent I want to consider, is there another one that I should discuss with my physician?

[AmberHunter]

i worked on one of the phase three clinical drug trials on paxil (paroxetine) back in 91... the drug was shown to be effective and safe. what wasn't known at that time by us researchers was that SSRI's have there own set of withdrawls symptoms (discontinuation syndrome) and can be very difficult to come off of. paxil appears to be the worst to come off of so if i were you (which i am not!) i would look into taking another SSRI or another class of AD. i switched from paxil to prozac b/c i had planned to discontinue the prozac which would be easier than discontinuing the paxil b/c prozac has a longer half life... so anyhow...

good luck with whatever choices you make and i am sure the doc will pop in here and answer your question as to whether it is contraindicated while on methadone!!

peace,

amber

[mrmichael67]

Methadone and Paxil are fine to take together.  This is a good site to check out:  http://www.drugdigest.org/DD/Interaction/ChooseDrugs
I also looked elsewhere and found no interactions anywhere else.

[Thomas050]

Hello all. I appologize for inturrupting this thread, but does anyone know why i can't post a new topic?? I have never been able to, it always says it has reached the daily limit. There are only two posts today!!
What is the trick to posting a new topic?
Thanks,
Thomas

[hippy]

Best to try between 830 am and 11 am eastern time,
in order to post a question

peace!!!!!!!!!!hippy

[Forum-M.D.-rcb]

Dear plumpkin:

I neglected to state that there is no listed contraindication to Paxil in Methadone maintenance to my knowledge

[AmberHunter]

come play with us on the other board! email me at: ***@****  doc, you are welcome there too!!! but i know you are busy as it is!!!

peace,

amber

[Huiler]

I've worked in a methadone clinic for a little over 2 years. Paxil seems to be the most prescribed drug for patients at my clinic who are seeing local psychiatrists.I've never heard of anyone complaining about the combination. (For what it's worth.)

[mrmichael67]

In what capacity did you or do you work at the clinic?

[Huiler]

I have been working as a counselor/case manager at this methadone clinic for a little over 2 years. Before that, I was working as a substance abuse counselor, mostly outpatient, since 1989. Why would you like to know?

[mrmichael67]

Your question on the other thread about what would help withdrawal off of methadone lead me to ask that question.  And, it causes me concern to see a counselor from a methadone clinic asking such a question.  If you were just the person who checks people in and takes payment, then I wouldn't think twice.

[Huiler]

Hi, Thanks for answereing my question. Yes, it is a problem for me too that we don't cirulate more good advice to our patients when they are trying to detox. I mean, the nurses and most everyone else, remcommends "very very slowly" to everyone, but other than that, they sort of mention diet and excerise. and that's about it. It is of much concern to me, because I want to see my patients succeeding when they get off the clinic. Not that I have a huge objection to some of those old-times being on methadone for life, except for the amount of money it costs everyone. Because I think an addiction brain is an addicted brain, and the right amount of opiates make the addicted brain a normal brain. Methadone is good because it takes you through the day. But the younger people - well, everyone really - why should they be on methadone the rest of their lives? Anyway, there's so much more to say, however, I can say it later. Can you really feel "yourself" after getting off methadone after being on it for months or years?

It is neat for me to read other points of view on these subjects. Regarding my clinic not seeming very wise, I don't want to seem cynical, but I've wondered. The answers I've gotten when inquring about more extensive information about withdrawal, comes down to, "Everybody's different." I respect my clinic a lot and I think it is ethical and fair, and I myself feel proud of the work I do, doing counseling and therapy with them - over a longer period of time than one usually gets a chance to do. I've seen some wonderful changes in people.

I hope you guys won't be mad to hear that a methadone counselor doesn't know everything about methadone, and won't turn me into some kind of a whipping post (those of you who don't like Methdadone.)

PS, I tried to post a question this morning 5/31/03 at 7 past 12:00 midnight, and it said they were all filed up. Go figure.

[mrmichael67]

I have no intentions of whipping you.  That is not my style.  But, I do think it is disturbing for a methadone clinic counselor to not know methadone like the back of their hand.  That would include getting off of it.  In all honesty, you are the one who should be fielding questions, not asking them.  It is cool you are making an effort to learn.  I do applaude you for that as a lot of counselors could give half a ****.  I am a mmt patient, so I know how it goes.  I have no disrespect for you.  I was just being honest in that I feel someone in your position should know it all about getting off of methadone, that's all.

[Huiler]

Yes, I agree with that, I SHOULD know all that. Since I don't, that's why I'm asking. My clinic seems to hire good sensitive, creaative, intelligent educated people, often with no addictions themselves, and lets them learn on the job. Life is full of people who are learning the jobs they are doing, I have found! But I Really Do want to help my patients with withdrawal, especially from 10 mg on down to getting off, and the next few weeks after that. I can't seem to get my own question going, so anyone who has any personal experience to share with me about what helped them, I would be Most Grateful for! Maybe I'll get my own question sometime.

[oxic]

Hi,

As Hippee mentioned above, it is best to try and post questions around 8:00 till 11:00 am Eastern.  There is a two question per day max(usually), except sometimes weekends will vary(sometimes only one or none at all).


percs

[peaz]

BUT!!!  On Thursdays it is best to post between 3:00 AM and  3:02 AM  Greenwich time  but you may ONLY use lower case letters during that time.....and make sure you have a Mets hat on backwards while chewing Juicy Fruit....Mondays:  FAGGEDABOUDIT.   Fridays are the one day you may get to post, but of course, I'm not talking about THIS forum.......LOL

    Oxic----How the hell ARE you??  I'm going through Canuck withdrawl here.........:-)

[mrmichael67]

I'm speechless.

[oxic]

LMAO

...It's move day!!!!
Just having my coffee and off we go.........yeha.

Appears i'm in the penalty box, above.

You remember my friend with the liver/kidney deal a while back; well this week he woke up one morning coughing up large volumes of blood........another trip to ER, found blood clotting in his lungs and pneumonia.  He is on the mend again.  Another crazy week.

I hope you are having a great weekend; and maybe we should break the "silence" this week???

I'll mail u en la manana.

[bmac]

Oh My God! I can't beieve this place,  God, GET A ROOM howabouit!
LOL JK Oh I forgot I already have one! Excuse me

[MethMan]

Yeah!  That display of affection was an abomination!  And in a public forum like this?  Yes, get a room!
Damn.  A guy gets his MIL outta the way and PRESTO, these groupies come out of the woodwork.
Bill, I appologize for their behavior.  Simply unacceptable.

[bmac]

Thanks for watching my back. Groupies are one thing I am usually watching for, but this?????????????? Man, watup wit dat?
I guess we'll have to add 'Canadian' to our vocabulary now! LOL

[Chezz2]

I hope all is well in the north.

So sorry to hear about your buddy. I hope everything works out for him. It is hard to hear stories like that and just wish that there was something you could do to ease the pain.

Chezzz

[oxic]

Hey Guys, I'm just clearing space so we can have that Reunion(or Union i guess) this summer.  

Chezz, thanks for the kind words!  Everything up here is cruising along.  My buddy has been through more than most people will ever go thru, and he still doesn't *****.  He is a tough mother ******, so i'm sure he'll pull through.
MIL is doing well, and as of right now....in her own apartment and working up here....waiting for her immigration to go thru.
Sober just over 7 months for her!!!

Still dealing with my buddys' estate "stuff", and that seems to pull me down every time,but trying to move forward.


I hope your hangin in my almost Canadian friend!!!  Always great to see you posting!!!


percs

[bmac]

(Don't say union around Peaz)!  LOL
Oh I am in trouble now.............

[Chezz2]

Percs,

You are a testament to those people out there that think they can't go on in life without the aid of opiates to "help" you get through the hard times.
You have been through the worst and still have made it through pill free. CONGRATULATIONS are in order.
I am so happy to hear about your MIL. YOU have a lot of involvement in why she succeeded, you should be proud of that. Cause I know I am envious of you to be able to help someone go from the depths of despair to recovery and beyond, all with your help.

Keep it up Buddy,
Chezz