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I have no drive to do anything.

I was on fentanyl and hydrococone for a bit over a year. Pain from MS. 3 months ago I wheened off the opiates and started taking high doses of neurotin. I first need to say thank you to all of you. I seem to have no interest in anything. No drive. Could this be my brain chemistry rebounding, or is this neurotin doing something to me. Just trying to find me again.
2 Responses
1801781 tn?1461629469
You have to remember how opiates work, and why you feel depressed etc. when you quit taking them and after you are over the withdrawals and often why we keep craving long after the physical withdrawals are over.

Opiates bound to the opioid receptors in your brain and body. They release their artificial endorphins to them, and block the bodies natural endorphins. After a while the neurons that produce the body's natural endorphins disappear. There is no need for them so they just don't rejuvenate like they would normally.

When you stop taking the opiates,  they leave your opioid receptors bare, and they are calling out for your body's natural endorphins, but there isn't any there at first. You body has to repopulate the neurons that make them, and this takes time.

Endorphins like dopamine  control your moods, anxiety, sadness, anger, happiness, pain etc.

You will slowly get your "old self" back as these neurons repopulate and begin increasing their endorphins production. After being off the opiates for a month, they should be about 45-50% of normal, and be back to normal within a year.
So hang in there, you will feel better and better as the months roll by.

Try keep busy and keep your mind focused on positive things instead of dwelling on the depression, anxiety, etc. that are only temporary and will disappear as your endorphins return to normal.

Avatar universal

       You have to give your brain time to start working without the drugs.  Drink plenty of water and gatorade if you can get it eat fish cooked in canola oil.  And eat some vegtables and fruits. And try a multivitamin This will restore your system faster.
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