Is it safe to take a Vicodin while I'm in Zoloft withdrawal?

[Scarface94]

Today I took 1 Vicodin (Labeled M367, 10/325 norco) I took my last Zoloft 14 days ago. I was on 50 mg Zoloft. I took my first Zoloft pill on December 19, 2014 and I took my last Zoloft pill on January 19, 2015.

I'm currently going through Zoloft withdrawals and have many of the typical Zoloft withdrawal symptoms. I was just wondering if taking a Vicodin will interfere with the recovery of my Zoloft withdrawal? Could I have done any permanent brain damage from taking a Vicodin since my brain is in recovery mode? This is the first Vicodin I have taken since I stopped taking the Zoloft.

[Scarface94]

I just took one because I had a stomach cramp from the Zoloft withdrawal.

[dominosarah]

Why do you need vicodin?

[Scarface94]

Don't they both lower dopamine levels though?

[RobbieNP]

Short answer: Yes it is safe.

Long answer: Vicodin contains paracetamol & hydrocodone, and Zoloft contains sertraline. paracetamol is a non-opioid analgesic, hydrocodone is an opioid, and sertaline is a selective serotonin reuptake inhibitor (SSRI). These classes of drug do not react with each other.