I'm not sure about methadone but I did cold turkey from suboxone and I've heard they're similar. There were a few things I was told to such as taking a really good multivitamin. Potassium, iron, and good vitamin c! Like the vitamin c packets. Epsom salt baths helped immensely! Rest, rest and REST!! Motrin 200mg 's 3 for sure. Are you alone in this or do you have any help?