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A family member of mine started developing paranoid feelings and thought it was from the medication she was taking.  ( 8-10 pills of oxycodone per day ).  So she lessened her dose greatly ( 2-3 pills per day ) as a result of her fear and also developed additional withdrawl symptoms such as insomnia, loss of appetite, muscle spasms, etc.  Although she will say the paranoia is a result of the withdrawl symptoms, I know she was experiencing this paranoia as well as some depression before she lessened her dose.  Could this be her body reacting to the longevity of her use of the oxycodone?
5 Responses
Avatar universal
How long was she using it and what for?

I doubt any feelings of paranoia came from oxycodone, but anything is possible.
Avatar universal
Well, she has been using it for severe pain she has as a result
of a chronic condition she has.  I would guess she has been taking it for about 1 year.  I am just worried that the paranoia is from something else because she has a history of depression and suffered from schizophrenia a few years ago.
Avatar universal
If this person has suffered from paranoia before the oxycodone, it is likely that whatever was causing that before may be returning.

If she carried a diagnosis of schiziphrenia, it is important to be aware that schizophrenia is a life long, genetically caused mental condition that needs on going management.  Paranoia is one of the symptoms of schizophrenia.  I would encourage her to get an evaluation by a mental health professional to see if she needs to be treated.

good luck!
Avatar universal
Depression & Schiz? Wow!

Getting off this stuff absent depression is almost impossible. I've found that taking just the same amount of this stuff every day ONLY as prescribed is the only possible way of co-existing with this medication.
Avatar universal
I have been taking oxycodone along with other painkillers and tranquilizers steadily for about a solid year now( was up to 12 a day) and during a recent withdrawal I did experience paranoia and depression and still do when I stop using for more than 12 hours.  Very unpleasant.
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