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takin methadone for oxy withdraws

im starting to take methadone to stop oxycontin withdraws. 1st.is, will taking methadone instead of oxycontin detox me from oxy,and how long till i can stop taking methadone and not feel any withdraws from oxy? 2nd how long does it take to become physically dependent on methadone?  im **** this myself no doc im getting it off the street. my goal is to stop physical dependence(withdraw) to oxy but not take methadone long enough to get physical dependence. i was taking 160mg of oxy a day, now im taking 30mg. methadone for the last 4 days and no oxy.
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Avatar universal
Hey Melroy,

I think that you may misunderstand the physical addiction process of opioids.

Opioid agonists (like oxy and methadone), are all agonists of the mu opioid receptors.  They all cause mu receptor axons to activate, firing a pulse of electricity.  The various and sundry opioids do this with varying degrees of effectiveness, which explains a substantial portion of their varying degrees of potency (liver metabolism makes up for the other portion).  For instance, this largely explains why dihydromorphone HCL (Dilaudid) is about 5 times the potency of oxycodone (Oxycontin) when taken orally, it stimulates mu more effectively.  In the case of good old-fashioned morphine via the oral route of administration, it is the first-pass effect of the liver, i.e. liver function, that largely determines its effectiveness.  But I digress...

Physical addiction occurs because the brain tries to compensate for the massively increased mu receptor activity by decreasing the sensitivity of the neurons that are on the other end of those axons, requiring increased firing frequency to generate the same effect that less frequent firing activity previously did.  When an oxycodone addict switches to methadone, the methadone keeps the receptors firing at the same rate that the oxycodone was (or only a slightly reduced rate).  When they then quit the methadone the endogenous (naturally occurring in the brain) opioid agonists, mainly endorphins (endogenous morphine), are insufficient to trigger the now desensitized neurons.  After a length of time clean, the brain resensitizes itself via the same mechanism that caused the desensitization.  Until that happens, though, the mu receptors do not fire as often as they should, and the owner of the brain feels like **** as a result.

So, in a nutshell, your WD symptoms are going to appear in any event, but the particular opioid that you are addicted to will impact the exact nature of the WD, due to its own unique properties with regard to its own metabolization within your body.  It is for this reason that I recommended that it is *MUCH* more desirable to taper using oxy, or even kick c/t from oxy(or other short-acting opioids) when compared to methadone.  Methadone is an ugly opioid, with a really long and nasty metabolization cycle, so please be careful with it.

I hope that helps!  If you have any more questions feel free to ask, and again, I wish you all the best.

Ray
Helpful - 1
1 Comments
Oxy withdrawl is not as bad as Methadone. Anyway, my question is how long can I expect to have withdraws from methadone. I was on it over 10 years. When I finally took the leap, I was on 2.5mg down from 30mg in just over a month.
Avatar universal
yes methadone works but you have to know how to take it .  first day take three 10mg as late in the afternoon as you can take 2 and about 7 or 8pm take the 3rd one    . 2nd day take 2 1/2  one in the late morning and 1 1/2 about 6pm     ,day 3  take two 10mg  one about 11am the other about 6pm , 4th day one and 1/2    take 1/2  around noon  and around 5pm take a full one
5th day Take one 10mg at any time  ,day 6 take 1/2 at any time  , day 7 take  1/2 of a 1/2 at any time  and i promise that  99.99% of the time your bodywill not withdraw . But thats not the only thing you have to do you have to jog and if you cant jog walking is fine but you have to movie them legs. and i just would like for you guys to know that this is just for body withdraws :( like body aches, restless legs, cold wets and those sleepless nites )  the hardest is the mental part of the process because you are going to have to learn how to live without pills and for most thats where we found our strength ,our happy place but just remember that wasent you that was the pills . beloveds i hope this helps and stay busy ,eat right and remember 1 day at a time !  ps very importent to move(jog or walk) and stretch them leg stay positive and may the God The Father be with you God bless
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Avatar universal
I have been trying to taper off oxys for about a month and a half I use methadone for like four days goin from 40mg down to 10 n after a day ended using oxy for couple days done this three times now.kept my using s secret but cant do it alone so came clean with my wife if I had like 110 mg of liquid methadone any advise on how to use that to get through physical wd n do I have to worry about methadone wd at this point any advise deeply thankful and when should start
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Avatar universal
I take methadone for about 2 to 3 days after stoping oxy. I don't get wd's from methadone. I hear they are brutal though. So just take it for a few days. Once you stop the meth it lasts into the next day and can help. Problem is that it gets you high and if you're an addict you ain't gonna stop. But oxy withdrawals suck. I hate the agitation. Can't stop moving can't sleep. I've had bad oxy withdrawal and heroin withdrawal but the worst withdrawal I've ever had was a nasty little pill called ultram or tramadol. Actually made me cry and sent me to the ER. Makes me shiver just thinking about it.
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Avatar universal
longer acting opiates, such as methadone, if used for a very brief period (3-5 days) can be very effective. I will explain why in my next post. gotta run
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2514305 tn?1339697760
LoL, It was not created by Hitler for mind control. I was created by Nazi scientists in 1937 because Germany's armed forces had no access to morphine for their troops, thus Germany's scientists formulated Methadone to distribute to soldiers that were horribly wounded or dying.
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2202447 tn?1338748214
I was addicted to dones for 3 months, about 20 mg a day, sometimes more. At the last week of use, I was at about 50 a day. I quit cold turkey and had hellacious withdrawels for 2 weeks. But anyway got through them, the last 2 days I took about 50 mls a day and today I took 20, not takin any more for a while. Am I gonna have wds this time, since I only used for 3 days? Please let me know?
Helpful - 0
1826775 tn?1321633072
broken back, spinal fusion surgery...pain clinic had me on:  40 mg of perc, day, 50 mg methadone per day, lyrics and baclofen.  Friday i go in and the counselor tells me he's taking me off methadone and switching me to opana (30mg 2X day) but no weening off methadone, just stop, i think he may be a little crazy!  I have read quite a bit about getting of the 'dones' and it seems pretty radical to just stop, i know the opana and perc. will alleviate the withdrawals but i am already feeling very bad.  the withdrawals on top of my regular pain levels is extraordinary.  I'm reading these symptoms get worse by the day until you peak then start to taper down.  I had been on 50 mg of methadone per day for 9 weeks and now i am suppose to take zero, this seems like torture at this point!! Anybody have any suggestions? ( I did stash a few for this exact reason but taking 1 or two from the 5 a day i was on still leaves me with tremendous misery!) I do want off though, i do not want to be dependent on any drug in my life.  I have a very good pain tolerance however, this is getting ridiculous.
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Avatar universal
Im on my 2nd detox and failed.im only on 45 of Meth. If the devil were to do drugs this is the one he would take.The withdrawl is horrible, no sleep stomach ache , legs,  so i am on maitenance now. in 2 weeks i will go down 1mg every week insteadof 5 every 9 days.We will see what happens. My only drug of choice was perc 10 and vics, and thats only because of an accident, i didnt do it for fun. I never did heroin,coke.pot. ANYTHING.just perc 10s. (about 15 a day). So if you can get off the METHADONE or stay on a very low dose. The MORE you take The harde it is to get OFF!!!!!!!!!
GOOD LUCK ALL.
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1826775 tn?1321633072
I was in a bad boating accident on sept 5, 2011.  My injuries are two crushed vertabrae(T5-T6), 3 broken ribs, and pneumothorax (collapsed lung).  I had spinal fusion surgery in which they fused 6 vertabrae (T3-T8) and inserted 12 screws and 2 titanium rods to support the crushed vertabrae and discs.  I am very fortunate to be alive and (according to surgeons) it is a miracle that I AM able to walk.  Very slowly for now but I am walking.  This is creating extraordinary pain levels, and the pain is constant.  I have been placed in a pain management clinic.  They have perscribed me 10 mg percocet (which do not seem to reduce the pain very well, and 50mg of methadone per day.  I am very concerned about the methadone as I have read horror stories about getting off this narcotic, Ive been on these meds for 3 wks and need some feedback.  The methadone doesnt seem to do anything for the pain, however, I am told i need to stay on it.  Anyone have any feedback for me??
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Avatar universal
HI YOUR plan sounds solid where not aloud to give taper schedules on the open forum but just take a little less every few days slow is good when tapering a pill cutter is handy if you do it like you say you should come off it the right way its the methadone that going to su ck to get off of really no good way to do that .....taper it down to nothing then jump and be ready for some heavy withdrawals but I was in the exaxt same situation as you and it is worth the pain and agony to be free from the ball and chain its nice thinking clearly again if you have any questions just message me good luck and God bless......Gnarly  
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Avatar universal
hello my question is as follows.......my dr had me on percs for a back problem.. I was on 5mg 3 times a day for about 6 months, after that time he put me up to 7.5 mg 3 times a day for about 4 months.  2 months ago he recommennded i see a pain managment dr instead of him.  So i started going to one and he after seeing my MRI and reports put me on 30 mg's of Roxicette 3 times a day plus 10 mg of methadone 3 times a day.  Ive gotta to the point where im taking these pills because of the pain and i follow the drs direction 100%.  Im only 29 years old and I am seeing how and what people mean when they say they take over your life!!  I have a great job, im engaged and have a 3year old daughter.I dont get them off the street because i follow the direction correctly.  So my question is if i stop taking the Roxicette cold turkey and just take the methadone  to slow  my body down then reduce myself off the methadone is that an intelligent way to approach this?? I know I'll still have withdraws at some point it just depend because of which drug.  since ive only been taking Roxicette for a few months and i have alot of methadone to help me do you think the withdraws will be as severe as someone who has been doing them for years or does it not matter legnth of time the with draws are the same no matter what?? I know its alot but if you could provide me with some serious, intelligent answers i would definetly appreiciate the feed back thanks you some much!!!  James fom NJ
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Avatar universal
i started takin oxys on vacation wen i hurt my neck, was takin about 40mg a day for teh first week then up to 60-100 by the end of the month. then i ran out a week before i left for home so went through the cold turkey withdraw, then gt back home and took about 120 to 160 a day, but then i slowly weend off cuzi realized how bad this was killin me not to menchin fukin expensive, now ill take 40-60 at a time, once a day, usualy in the afternoon. soo its been about 2-3 months with oxy, how bad would the withdraw be for cold turkey? and hten finally be done for good? i love workin out which makes me feel good, used to wrestle and watnot. im also prescribed xanax and adderal for my add and panic/anxiety disorder. i have gone a day or two wtihout oxy and id take extra xanax or i would take lots and lots of calming teas/supps liek theanin, gaba.
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401095 tn?1351391770
30 mg for 2 weeks..chance r u r ok..but evreyone is different...cut back 5mg a day and be done by sunday.dont get stuck on the methadone...just as people seem to get stuck on sub..it is narcotic invented for pain that did not have the intense high associated with othe narcs..just as sb does not...made in it germany for pain releief...The USA made it a detox drug with a bad name attached to it...many elderly use it to control chronic pain...it really no stronger than oxy and much less strong than sub by compariosn..1 mg sub - 15-20 mg of methadone...not pushing either..sub will burn u quick..methadone will burn u too..u wake up addicted and neither are easy wds...due to the long half life of both sub and meth....get on off..taper on down..and be clean..get some aftercare
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Avatar universal
Im 21 years old and have been abusing drugs since i was in eigth grade with marijuana, then the good ol hey try this white stuff makes u feel great! then i graduated to full blown nething and everything.. Ive been switching from being addicted severely to pain killers, back to snorting /smokin cocaine, " which to say i jacked my dealer to trade for oc" so I know that its the worst thing ever.. But neways, After a couple years of abuse i went to a clinic, mostly to be stable, but i still wanted to get high, 6 months at 80 mgs and i went off it CT it was WAY worse then 3 little ***** days of oc withdrawls that mostly just **** with you mind, so STAY OF DONES, I SHOULDVE tapered but couldnt afford commute so i took my last dose,, Exactly 3 days later  my stomach felt like someone was stabbing it with knifes.. about 30 days later i got back to somewhat normal after A severe hell.> was sober of pills for 6 months, got some drank for my cough went down hill from there.. 2 days of oc at atleast a 80 a day if not more and I am already starting to feel somewhat better, but im also drinking beer right now.> neways point being stay the **** off drugs everyone, and if u need to get off , GROW SOME BALLS AND DO IT.. gotta do it sooner or later, **** methadone and sub its all a crutch and goverment way of getting u hooked but keeping u a functioning zombie, and neone who wants to say ooh i would have done this or that if i dont have it, CAUSE UR A ADDICT GO TO FUCING REHAB
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333612 tn?1302883390
This post is almost a year old. These people are not here anymore.
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Avatar universal
I was on oxys for three months. took meth for five days going down 5 mgs a day. I did not have any withdrawals from oxys. after 5 days I was not dependent on meth and did not have any withdrawals from meth. I was off both pills in less then a week for good
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Avatar universal
wow im reading all of this and just thinking what is this world coming to.  I have been on methadone for almost three years and its the hardest thing ive ever had to deal with the ups the downs some days penuts and some days shells but one thing i do know is that getting off of on drug and starting on methadone is not the answer let me say the thing that does work well for me personally is that fact that meth makes me function very normally in life i can live a very normal life.  I just wish i could explain it better but i guess you would have to knoe me to understand i do no that methadone keeps your head straight it keeps me productive not wanting to do any drugs whether it be any other pills or cocaine or even herion ive done them all they make me not have any interest in any other drug it really makes me feel like i can be very productive ive tried though to get off of it at times because of feeling guilty but why feel guilty when it keeps me normal ive lived the last three years with know problems but every time i do try to get off because of guilt its all but the hardest thing ive ever had to do it sucks and is hard so as of today im on 50 mgs aday and i get it from someone else and that in itself sucks but i do what i do through life to get by but one thing i dont suggest is going from one heavy drug to methadone
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Avatar universal
do somas and or tylenol 3 with with oxycontin withdraws?  how long can valium be detected in urine drug test?  thank u fall your info.!!!!!
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Avatar universal
how about somas???? i i have a bottle of lyrica and valium. somas r cheap and easy to get.  i cant c a doc cant afford it no insurance.   thank u again fro the info.
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Avatar universal
Hey Melroy,

Sorry, been away for a bit, we are having a spot of weather up here and things have been a bit hectic.

OK, let me preface by saying that I am not an MD, no do I have any specific medical training.  I have a formal CS background and am a computer programmer by trade.  I do have an interest in chemistry/pharmacology, but it is strictly a hobby.  I am an opioid addict.

My first bit of advice, would be to consult a doc about the whole thing.  Depending on your circumstances, perhaps a doc that is not your usual GP.  Also, if you are getting your oxy through legitimate channels, by Rx, *NEVER, EVER* tell your prescribing doc that you are having a problem, or that you are no longer in pain.  Kick, keep it quiet, and keep the Rx flowing.  Hoard the stuff in a strongbox, safe, whatever.  Reason being, should you relapse after tanking your Rx, you will be forced to the street to score for all your needs.  So, give your sanity (and wallet) a break and keep everything on the down and low.  :)

So, yeah, I would recommend that you see a doc, discuss everything with him/her.

Now, I am not familiar with all of your circumstances, but I reckon that you have two front and center options here.  Cold turkey or a taper, both, preferably from the oxy (or short-acting opioid).  Personally I prefer hydromorphone, I find it somewhat less "edgy".

So, with regard to your methadone to oxy switch question, I would say to take a smallish dose of oxy, and see where that leaves you.  You said that you took 160mg per day.  What was your dosing schedule like?  I am guessing something like 40mg every 6 hours (just speculating)?  If that is the case, try starting with 20mg every 6 hours (for a total of 80mg per day).  If you do not feel sick, try lowering it the next day by 5mg per dose (as I said, this would be easier with percocet, as cutting up an oxy 40 into small bits could prove a real pain in the hind end).  So, yeah, lower each dose by 5, so 15mg every six hours.  What I am getting at here, is that you want to find the absolute lowest dose that will keep you from WD.  For example, if, at 15mg, you feel WD symptoms, go back to 20mg per dose.  Now, stabilize at this dose for a few days.  Then begin your taper.  Try and taper your dose at a rate of about 20% per week.  You can shorten this time, but this will increase the likelihood of discomfort.  With tapering, slower is always better.  So continue this taper regiment until you are at a very low dose for a week, say 5mg every 6 hours, or preferably even less, lets say a half a percocet every 6 hours for one week.  Then quit.  You may still feel some WD, but it will be much less intense that kicking at 160mg per day.  Some feel almost nothing, maybe a case of the yawns and sniffles.

Now, with regard to your alcohol question, I would advise against it, at least in large quantities.  While it might take the edge off a bit, help you rest, and, perhaps most importantly, speed up your perception of the passage of time, you most certainly do not want to combine hangover with WD.  So don't overdo it. :)

Exercise.  As much as you can handle really.  I mean, don't go out and try and run a marathon, but if you can handle several brisk walks a day then by all means.  Fire in some sit-ups, etc.  Whatever you can reasonably handle.  It will also help pass time.

Lyrica may help with some of the anxiety and muscle cramping.  In addition, its sedative effect may prove useful in copping a few minutes sleep in those first few days.  Please note that Pfizer does warn of potential interaction with oxycodone, while taking both concurrently, so you may wish to look further into that.  After a quick glance, it seems to be no more than additional drowsiness and possibly slight confusion.  In any event, take a closer look at that.  Bring it up with the doc.

Just a quick additional note.  When it comes to cold turkey, I have never found a magic bullet that makes WD easy.  As another poster stated, it sucks, plain and simple.  I think accepting that is an important part of recovery.  That being said, I am always open to new ways that might mitigate the suffering.  The most glowing praise I have heard for a WD recipe was using two meds, Neurontin (gabapentin) and Doxepin.  I believe it was something like Neurontin 300mg PO q.i.d. x 5 days and Doxepin 50mg PO t.i.d. x 5 days (thats Neurontin 300mg 4 times daily for 5 days and Doxepin 50mg 3 times daily for 5 days).  According to the source, they were able to actually get pretty near a full night of sleep each night and the WD itself was described as almost painless.  Again, this is anecdotal evidence, so take it for what it is worth, also keeping in mind that WD is different for everybody.  And oh yes, rent a bunch of DVDs, mindless fun stuff, and get comfy. :)

All the best, keep us posted, and if you have any more questions, feel free to fire away!  

R

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Avatar universal
All,

I can't help noticing how many folks replace one drug with another to avoid w/d from the first, etc., etc. Now, I don'tprofess to know the answers, what's more I think there are many ways to succeed BUT I suggest considering the following:

1. Biteing the bullet and endure feeling terrible (whether taper or c/t)

2. If you are concerned for your safety while in w/d, go to a Detix where they will keep you SAFE and comfortable.

3. And/OR if you feel that you can't endure the w/d, go to Detox.

It is my strong assertion that replaceing oxy with methadone is NOT the way to go. That's a 'dance with the devil' (so to speak, I don't mean it's a sin or anything). And street drugs are very dangerous (and I do NOT mean this in a judgemental way--I used them too!) and, if we are working so hard to get better and progress I truly beleive that these tactics are not congruous with that.

That said, I WELCOME EVERYONE and invite everyone to share their views. And no matter folks decide, our support is absolutely unconditional and not predicated upon someone following a suggestion offered up to them in a post. :)

Jessica
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Avatar universal
there was a comment that said that excercise help how much and y?
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Avatar universal
damn   does beer help or does it make it worst
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