I've been told to go on prednisolone for 3 months or so in order to bring down my slightly elevated liver enzymes. I am worried that the prednisolone might react with the oroxine therapy which I am taking daily for my Hashimotos hypothyroidism. The amount of prednisolone is 25mg per day for 1 week, then 10 mg per day for 2 weeks, then 7.5mg per day for 4 weeks, then 5 mg per day until i see the doctor in 3 months time. The liver doctor has also put me on ursodeoxycholic acid tablets 1 tablet two times a day. I don't want to start on the prednisolone therapy unless it is absolutely necessary & I don't know if it goes with oroxine. I'm concerned about the effects on my health.