High ACTH and cortisol

[woodshoes]

My ACTH test is 53 range 6-50 cortisol is 25 range 6-22 is this considered high? Doc is looking for my bad fatigue problem. Going by rumpled my ACTH test was not done in a chilled tube so am going to have it redone. So far had 24 hour urine high cortisol dexa blood draw high. Also MRI on pituary nothing showed but read rumpled post saying they can be hidden . My doc wants to see disc of MRI don't trust radiologist. Now she wants to do a PET scan full body I guess looking for cancer are my levels high enough to look for cancer? Tonite am doing a midnight saliva test two nights running to test for cortisol. Is all these tests going to show something? Meantime my fatigue is terrible I also have hashimotos and diabetes 2. Thyroid levels are low still trying to get them up could be some of the fatigue.

[rumpled]

Tiny pituitary lesions can hide. Was your scan dynamic? Did you get a surgeon to read films?

I also had an ocreotide scan. They could test you for neuro endocrine tumors.

[woodshoes]

Had pet scan nothing there still have high cortisol. What test is there for a tiny pituary tumor that's missed by the MRI? The fatigue is awful.

[rumpled]

Usual endocrine issues are not associated with cancer... I did get a pet scan but only after my ACTH skyrocketed where it could have been an ectopic source.

Your doc must have a reason for the test hope all is well.

Post back when you know more.