Adrenal Insufficiency Community
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elevated 17-hydroxyprogesterone test?

I just had some tests done and the 17-hydroxyprogesterone test came back elevated. I am now going to do an ACTH stimulation test. Does anyone know anything about non classical adrenal hyperplasia?????
I suffer from high testosterone, irregular periods, hypothyroid, depression, etc......could this all be related to the adrenal glands?????? I am really confused about all of this!!!!

Please help me!
4 Responses
Avatar universal
sorry, the test was done on the 3rd day of my period and it was 232.
Avatar universal
I recently got test results that showed elevated levels of 17 hydroxyprogesterone and have all the symptoms/characteristics you describe.

How were you treated for this?  What did it end up being?
Avatar universal
I found this on the internet:
"Non-classical(NCAH) (also known as Late-Onset CAH) is a variation of CAH that can begin to cause noticeable changes at any time from early childhood through early adulthood but is not immediately life-threatening. NCAH can have a range of symptoms which overlap with other disorders and therefore may not be easily diagnosed, and so is less likely to be diagnosed promptly.

Girls born with NCAH have normal genitals. Boys also appear normal. Because the symptoms begin later in life, NCAH is sometimes called late-onset CAH, adult-onset CAH, or the attenuated form of CAH. Non-classical CAH does not progress to classical CAH in affected individuals.

NCAH may be picked up in infants through newborn screening tests, but they do not necessarily need treatment. Parents can be aware of the symptoms of the disorder and seek treatment if it becomes necessary. Only those children/adults who are symptomatic should be treated. Some with NCAH never experience bothersome symptoms. Those with NCAH who have no symptoms do not need treatment.

What are the symptoms of NCAH?
NCAH symptoms vary from person to person. Also, one person’s symptoms may come and go over time. These symptoms can begin at any time in life and may start in early childhood. These symptoms are often mistaken for premature puberty - girls with signs of puberty before age 8 and boys before age 9. It is progressive, meaning that the untreated symptoms may become worse over time."

The treatment is generally one of the forms of long acting corticosteroids like dexamethasone or prednisone.

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