I was given 50mg prednisone at the ER on Sunday 3am, following a delayed reaction to penicillin. I proceeded to take 50mg daily until I started feeling horrible (today) I asked the pharmacist and she told me to stop if I felt palpitations and high blood pressure which is exactly what i felt. I noticed now 14hrs later my rash is coming back and i feel my throat pulsating (not sure if that's from palpitations of carotid artery) or if i'm closing up again, slowly? I haven't taken benadryl in over 24hrs either because I felt taking all these medications was making me feel bad and I figured since my skin looked normal the reaction was over. I took the missed dose of prednisone now and my next dose is at 11am is that too early for the next one? What should I do if I continue feeling palpitations in my throat? My bp was higher than normal today 129/80 and my heart rate was 123bpm (i'm only 20 in fairly good health usually 111-116/80-90, usually 81bpm) Should i take benadryl again? I've taken prednisone in the past, only once for another allergic reaction and I don't remember it affecting me like this. I'm still breathing just barely wheezing. I'd appreciate any advice ASAP as i'm a little nervous.