I have a case of long-term cluster hives (8 months) every single day. I have been to five different medical specialists (Rheumatologist, Dermatologist, Allergist/Immunologist, Internist, DO) and none of these doctors have been able to diagnose the cause of the problem. I have had two biopsies, all allergy tests, tests for Lupus and other diseases and all results were negative. I am now on a course of Prednisone (10 mg day) which is helping the hives but is causing other problems such as moon face and depression. Is there anywhere else to turn. I'm out of ideas. Thanks, Malka